摘要
目的探究不同手术方式治疗甲状腺结节的临床效果。方法选取2017年1月至2020年7月本院收治的80例甲状腺结节患者作为研究对象,随机分为对照组与观察组,每组40例。对照组行传统甲状腺切除术治疗,观察组行改良小切口甲状腺切除术治疗。比较两组手术指标、治疗前后甲状腺功能指标[血清促甲状腺激素(TSH)、总三碘甲状腺原氨酸(TT_(3))、总甲状腺素(TT_(4))、游离三碘甲状腺原氨酸(FT_(3))、游离四碘甲状腺原氨酸(FT_(4))]、生活质量综合评估问卷(GQOL-74)评分及并发症发生率。结果观察组术中出血量少于对照组,手术时间、切口长度、术后肛门排气时间及住院时间均短于对照组,差异有统计学意义(P<0.05)。术后3个月,两组血清TSH水平均高于术前,血清TT_(3)、TT_(4)、FT_(3)及FT_(4)水平均低于术前,差异有统计学意义(P<0.05);两组血清TSH、TT_(3)、TT_(4)、FT_(3)及FT_(4)水平比较差异无统计学意义。术后3个月,两组社会功能、躯体功能、心理功能及物质功能评分均高于术前,且观察组高于对照组,差异有统计学意义(P<0.05)。观察组术后并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论改良小切口甲状腺切除术治疗甲状腺结节效果显著,可明显缩短患者手术时间与住院时间,减少术中出血量,降低并发症发生率,提高患者生活质量,值得临床推广应用。
Objective To explore the clinical effect of different surgical methods in the treatment of thyroid nodules.Methods 80 patients with thyroid nodules admitted to our hospital from January 2017 to July 2020 were selected as the research subjects,and they were randomly divided into control group and observation group,with 40 cases in each group.The control group was treated with traditional thyroidectomy,and the observation group was treated with modified small incision thyroidectomy.The operation indexes,thyroid function indexes[serum thyroid stimulating hormone(TSH),total triiodothyronine(TT_(3)),total thyroxine(TT_(4)),free triiodothyronine(FT_(3)),free tetraiodothyronine(FT_(4))]before and after treatment,the scores of comprehensive quality of life assessment questionnaire(GQOL-74)and the incidence of complications were compared between the two groups.Results The intraoperative blood loss of the observation group was less than that of the control group,and the operation time,incision length,postoperative anus exhaust time and hospital stay were shorter than those of the control group,and the difference was statistically significant(P<0.05).3 months after operation,the serum TSH levels of the two groups were higher than those before the operation,and the serum TT_(3),TT_(4),FT_(3) and FT_(4) levels were lower than those before the operation,the difference was statistically significant(P<0.05);there was no significant difference in serum TSH,TT_(3),TT_(4),FT_(3) and FT_(4) levels between the two groups.At 3 months after operation,the scores of social function,physical function,psychological function and material function of the two groups were higher than those of preoperatively,and the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).The incidence of postoperative complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Modified small incision thyroidectomy has significant effect on the treatment of thyroid nodules,which can significantly shorten the operation time and hospital stay of patients,reduce intraoperative blood loss,reduce the incidence of complications,and improve the quality of life of patients,it is worthy of clinical application.
作者
尹波
杨鹏
李小辉
YIN Bo(Department of General Surgery,Ganxi Cancer Hospital,Pingxiang,Jiangxi,337000,China)
出处
《当代医学》
2021年第34期63-66,共4页
Contemporary Medicine
