摘要
目的探究肠内营养支持对ICU重症肺炎患者血气指标和凝血功能的影响。方法选择重症肺炎患者100例,随机纳入对照组和观察组,各50例。对照组接受肠外营养支持,观察组接受肠内营养支持,2组均治疗1周,并随访2周。比较2组治疗后疗效,治疗前后血气指标、凝血功能、APACHEⅡ评分,随访2周后机械通气指标。结果治疗后,观察组总有效率(84.00%,42/50)高于对照组(66.00%,33/50 P<0.05)。治疗后,2组PaO_(2)、SaO_(2)均较治疗前升高,且观察组高于对照组(P<0.05);APACHEⅡ评分、PaCO_(2)、血浆FIB较治疗前降低,且观察组低于对照组(P<0.05)。治疗后,2组APTT、PT与治疗前比较均延长,观察组长于对照组(P<0.05)。随访2周后,观察组撤机成功率高于对照组,VAP发生率低于对照组(P<0.05)。结论肠内营养支持治疗可改善重症肺炎患者凝血功能、血气指标及机械通气指标,疗效确切。
Objective To investigate the effects of the enteral nutritional support therapy on blood gas indexes and the coagulation function in ICU patients with severe pneumonia.Methods A total of 100 patients with severe pneumonia were randomly enrolled into a control group and an observation group,with 50 cases in each group.The control group received a parenteral nutrition support treatment,while the observation group received an enteral nutrition support therapy.Both groups were treated for one week,and followed up for two weeks.The efficacy,blood gas indexes,coagulation function,APACHE II scores before and after treatment,and the mechanical ventilation indexes after 2 weeks of follow-up were compared between the two groups.Results After treatment,the total effective rate of the observation group(84.00%,42/50)was higher than that of the control group(66.00%,33/50)(P<0.05).After treatment,the PaO_(2) and SaO_(2) levels in the two groups were increased compared with before treatment,and the observation group was higher than the control group(P<0.05).The APACHE II scores,the levels of PaCO_(2) and plasma FIB were lower than those before treatment,and the observation group were lower than the control group(P<0.05).After treatment,the APTT and PT were prolonged in both groups,and the observation group was longer than the control group(P<0.05).After 2 weeks of follow-up,the success rate of weaning in the observation group was higher than that in the control group,and the incidence of VAP was lower than that in the control group(P<0.05).Conclusion The enteral nutrition support therapy can improve the coagulation function,blood gas indexes and mechanical ventilation indexes in patients with severe pneumonia,with a remarkable curative effect.
作者
由丽丽
富丽
邓品
YOU Lili;FU Li;DENG Pin(Department of Critical Care Medicine,the Second Hospital of Chaoyang City,Chaoyang 122000,China)
出处
《长春中医药大学学报》
2021年第6期1375-1378,共4页
Journal of Changchun University of Chinese Medicine
基金
国家自然科学基金委员会资助项目(81770470)。
关键词
重症肺炎
肠内营养支持
凝血功能
血气指标
机械通气
severe pneumonia
enteral nutrition support therapy
coagulation function
blood gas index
mechanical ventilation
