摘要
目的研讨腰椎手术患者应用右美托咪定复合丙泊酚全麻对其镇痛效果的影响。方法研究对象为2019年8月—2021年4月于该院进行腰椎手术的患者86例,采用随机抽签法按1∶1的比例分配,将组别名称设定为对照组与研究组,对照组对患者应用的方式为麻醉诱导前静脉泵入生理盐水,研究组对患者应用的方式为麻醉诱导前静脉泵入右美托咪定,分析两组患者麻醉后的效果以及其不良反应。结果研究组收缩压(SBP)、舒张压(DBP)以及心率(HR)指标在插管1 min后数据分别为(110.23±13.36)mmHg、(68.14±7.43)mmHg及(67.12±6.61)次/min,与对照组对比,差异有统计学意义(t=4.447、4.891、8.257,P<0.05);研究组拔管1 h后SBP、DBP及HR分别为(124.35±14.35)mmHg、(75.07±7.88)mmHg、(68.43±6.74)次/min,与对照组对比,差异有统计学意义(t=4.212、2.058、7.727,P<0.05);研究组术后2、24、48 h时间段的VAS评分分别为(2.98±1.01)分、(2.94±1.02)分、(3.01±0.97)分,均明显低于对照组,差异有统计学意义(t=4.320、4.433、5.136,P<0.05);研究组不良反应发生率为13.9%,与对照组对比,差异有统计学意义(χ^(2)=4.169,P=0.041)。结论应用右美托咪定复合丙泊酚为腰椎患者施以全麻操作,能够降低对患者血流动力学的影响,提升其镇痛与镇静的效果,对于患者临床治疗具有重要价值,值得在临床中大力推广。
Objective To study the effect of general anesthesia combined with dexmedetomidine and propofol on the analgesic effect of patients undergoing lumbar spine surgery.Methods The subjects of the study were 86 patients who underwent lumbar spine surgery in the hospital from August 2019 to April 2021.The random lottery method was used to allocate the groups at a ratio of 1:1,and the names of the groups were set as the control group and the study group.The control group used intravenous pumping of normal saline before anesthesia induction,and the study group used intravenous pumping of dexmedetomidine before anesthesia induction.Analyzed the effects of anesthesia and adverse reactions of the two groups of patients.Results The data of systolic blood pressure(SBP),diastolic blood pressure(DBP)and heart rate(HR)indicators in the study group after 1 minute intubation were(110.23±13.36)mmHg,(68.14±7.43)mmHg,and(67.12±6.61)times/min.Compared with the control group,the difference was statistically significant(t=4.447,4.891,8.257,P<0.05).The SBP,DBP,and HR of the study group were(124.35±14.35)mmHg,(75.07±7.88)mmHg,and(68.43±6.74)times/min after extubation 1 h,which had obvious advantages compared with the control group,the difference was statistically significant(t=4.212,2.058,7.727,P<0.05).The VAS scores of the study group at 2 h,24 h,and 48 h were(2.98±1.01)points,(2.94±1.02)points,and(3.01±0.97)points respectively,which were significantly lower than those of the control group,the difference was statistically significant(t=4.320,4.433,5.136,P<0.05).The incidence of adverse reactions in the study group was 13.9%,which was a significant advantage compared with the control group,the difference was statistically significant(χ^(2)=4.169,P=0.041).Conclusion Applying dexmedetomidine combined with propofol to perform general anesthesia for lumbar patients can reduce the impact on the patient's hemodynamics and improve its analgesic and sedative effects.It has important value for the clinical treatment of patients,and it is worthy of vigorous promotion in the clinic.
作者
张贵权
高秀敏
ZHANG Guiquan;GAO Xiumin(Department of Anesthesiology,the Third People's Hospital of Honghe Prefecture,Gejiu,Yunnan Province,661000 China)
出处
《系统医学》
2021年第22期85-88,共4页
Systems Medicine
关键词
右美托咪定
丙泊酚
腰椎手术
镇痛
血流动力学
Dexmedetomidine
Propofol
Lumbar spine surgery
Analgesia
Hemodynamics
