摘要
目的探讨妊娠期糖尿病患者不同孕周接受胰岛素治疗对血糖水平、妊娠结局的改善作用。方法选取该院2020年1—12月收治的妊娠期糖尿病患者120例为研究对象,以治疗起始孕周的不同将患者分为两组,对照组治疗起始孕周≥32周,从孕周32周至分娩前行胰岛素治疗,观察组治疗起始孕周<32周,在孕周32周前行胰岛素治疗,对两组的血糖水平、妊娠结局进行对比。结果治疗前,两组患者空腹血糖、餐后2 h血糖水平及糖化血红蛋白水平比较,差异无统计学意义(P>0.05);治疗后,两组患者各指标水平均明显下降,但观察组各指标水平均低于对照组,差异有统计学意义(P<0.05)。两组剖宫产率对比,差异无统计学意义(P>0.05),观察组妊娠期高血压、产后出血、羊水过多、酮症等妊娠并发症发生率均低于对照组,差异有统计学意义(P<0.05);观察组各项新生儿并发症发生率均低于对照组,差异有统计学意义(P<0.05)。结论妊娠期糖尿病患者早期行胰岛素治疗效果相对于晚期治疗更为理想,可以更好地改善患者血糖水平,且可减少不良妊娠结局发生,可推广使用。
Objective To investigate the effect of insulin treatment in gestational diabetes patients at different gestational weeks on the improvement of blood glucose level and pregnancy outcome. Methods A total of 120 gestational diabetes patients admitted to the hospital from January to December 2020 were selected as the research objects. The patients were divided into two groups based on the difference of the initial gestational weeks of treatment. In the control group, the initial gestational age was ≥32 weeks, and insulin treatment was performed from the 32nd gestational age to before delivery. The observation group was treated with insulin treatment before 32 weeks of gestation. The blood glucose level and pregnancy outcome of the two groups were compared. Results Before treatment, there was no significant difference in fasting blood glucose, 2 h postprandial blood glucose levels, and glycosylated hemoglobin levels between the two groups of patients(P>0.05).After treatment, the levels of each index of the two groups of patients decreased significantly, but the levels of each index of the observation group were lower than those of the control group, and the difference was statistically significant(P<0.05).There was no statistically significant difference in the cesarean section rate between the two groups(P>0.05). The incidence of pregnancy complications such as hypertension, postpartum hemorrhage, polyhydramnios, and ketosis in the observation group were lower than those in the control group, and the difference was statistically significant(P<0.05). The incidence of neonatal complications in the observation group was lower than that in the control group, and the difference was statistically significant(P<0.05). Conclusion The effect of early insulin therapy in patients with gestational diabetes mellitus is more ideal than that of late treatment, which can better improve the patient’s blood sugar level, and can reduce the occurrence of adverse pregnancy outcomes. It can be popularized.
作者
张莹
ZHANG Ying(Department of Obstetrics,Shaxian District General Hospital,Sanming,Fujian Province,365500 China)
出处
《糖尿病新世界》
2021年第21期84-87,共4页
Diabetes New World Magazine
关键词
妊娠期糖尿病
胰岛素
孕周
妊娠解决
血糖水平
Gestational diabetes mellitus
Insulin
Gestational age
Pregnancy resolution
Blood glucose levels
