摘要
目的本研究旨在观察等压引流联合自拟五黄生肌汤创腔冲洗治疗多间隙肛周脓肿的临床疗效,探索中医药治疗多间隙肛周脓肿的应用。方法本研究纳入188例肛周脓肿患者,其中对照组149例,观察组39例,采用倾向评分匹配法获得基线资料平衡的两组患者各33例。对照组术后换药采用生理盐水冲洗创腔,观察组则采用五黄生肌汤冲洗创腔,根据两组患者创面渗液情况、肉芽生长情况、创面深度、创面愈合时间、腐肉脱落时间以及平均住院时间评价两组患者疗效。结果匹配后,两组患者基线资料对比差异无统计学意义(均P>0.05)。术后第7天,观察组渗液评分低于对照组,差异有统计学意义;术后第5、14天差异无统计学意义(均P>0.05)。肉芽生长评分比较中,术后第5、7、14、21天,两组患者比较差异均有统计学意义(均P<0.05)。创面深度比较,术后第14、21天,观察组及对照组比较差异有统计学意义(均P<0.05),而术后第7天比较差异无统计学意义(P>0.05)。观察组平均创面愈合时间为(33.27±3.43)d,对照组为(36.94±4.95)d,差异有统计学意义;腐肉脱落时间,观察组和对照组比较差异无统计学意义(P>0.05);观察组患者平均住院时间为(9.97±2.49)d,对照组为(12.88±3.58)d,差异有统计学意义(P<0.05)。结论肛周脓肿术后采用五黄生肌汤冲洗创腔,可促进创面生长,加速创面愈合,降低平均住院时间,效果优于生理盐水冲洗创腔。
Objective To observe the clinical efficacy of isobaric drainage combined with self⁃made WuhuangShengji Decoction wound cavity irrigation in the treatment of multi⁃space perianal abscess,and to explore the application of traditional Chinese medicine.Methods 188 patients with perianal abscess,including 149 in the control group and 39 in the observation group.Propensity score matching method was used to match the baseline of the two groups of patients.There were 33 patients enrolled in each of the two groups with balanced baseline data.The control group used normal saline to wash the wound after the dressing change,while the observation group used WuhuangShengji Decoction to wash the wound.The wound exudation,granulation growth,wound depth,wound healing time,and sloughing time of the wound in the two groups,as well as the hospitalization days,were used to evaluate the efficacy of the two groups of patients.Results After matching,there was no statistical difference in baseline data between the two groups(All P>0.05).At 7 days after operation,the score of the observation group was lower than that of the control group,the difference was statistically significant(P<0.05);at 5 days and 14 days,the difference was not statistically significant(all P>0.05).In the comparison of granulation growth scores,5 days after surgery,7 days after surgery,14 days after surgery and surgeryafter 21 days,the difference between the observation group and the control group was statistically significant(all P<0.05).In comparison of wound depth,14 days(and 21 days)after operation,the difference between the observation group and the control group was statistically significant(all P<0.05).However,there was no statistically significant difference in the index 7 days after operation(P>0.05).The average wound healing time of the observation group was(33.27±3.43)d,and the control group was(36.94±4.95)d,the difference was statistically significant.There was no significant difference in the time of carrion shedding between the observation group and the control group(P>0.05);the average hospital stay of the observation group was(9.97±2.49)d,and the control group was(12.88±3.58)d,the difference was statistically significant(P<0.05).Conclusion Following a perianal abscess,using WuhuangSh⁃engji Decoction to flush the wound cavity can promote wound growth,accelerate wound healing,and shorten the av⁃erage hospital stay.The effect is superior to standard saline irrigation of the wound cavity.
作者
徐兆宇
郅重阳
XU Zhaoyu;ZHI Chongyang(Department of Anorectal Sur-gery,Weifang Hospital of Traditional Chinese Medicine,Weifang 261041,China)
出处
《实用医学杂志》
CAS
北大核心
2021年第24期3208-3212,共5页
The Journal of Practical Medicine
基金
山东省皮肤性病学重点实验室科研资助项目(编号:ZDSYS201712)。
关键词
肛周脓肿
五黄生肌汤
倾向评分匹配法
perianal abscess
traditional chinese medicine
propensity score matching
