期刊文献+

论Klotho基因与肾主生殖生长发育的关系 被引量:5

Discussion the Relationship Between Klotho Gene and Kidneys Govern Reproduction Growth and Development
原文传递
导出
摘要 肾精和Klotho基因对生殖、生长发育均有着重要的作用。本文在前期研究提出了Klotho基因是肾精的重要组成之一。在此基础上,本文进一步探讨Klotho基因的生物学作用与肾精的先天之精、主生殖和生长发育的关系。 Kidney essence and Klotho gene play a significant role in reproduction,growth and development.In this paper,Klotho gene is one of the important components of kidney essence.On this basis,the relationship between the biological function of Klotho gene and the congenital essence,govern reproduction and growth,as well as development were further discussed to provide scientific basis for development of the theory of kidney govern reproduction and growth in TCM.
作者 王长江 邹新蓉 王岚 吴文静 程虹 王小琴 WANG Chang-jiang;ZOU Xin-rong;WANG Lan;WU Wen-jing;CHENG Hong;WANG Xiao-qin(Department of Nephrology y Hubei Provincial Hospital of TCM,Hubei,Wuhan,430061,China;Institute of Chinese Medicine Nephrology,Hubei Province Academy of Traditional Chinese Medicine,Hubei,Wuhan,430074,China;Affiliated Hospital of Hubei University of Traditional Chinese Medicine,Hubei,Wuhan,430061,China;Hubei University of Chinese Medicine,Hubei,Wuhan,430060,China)
出处 《贵州中医药大学学报》 2022年第1期1-4,共4页 Journal of Guizhou University of Traditional Chinese Medicine
基金 国家自然科学基金,项目编号:81874439,81703991,82074395 武汉市科技计划项目,项目编号:2019020701011456,2020020601012242。
关键词 KLOTHO基因 肾精 生殖 生长发育 Klotho Kidney essence Reproduction Growth and development
  • 相关文献

参考文献4

二级参考文献45

  • 1黄琼霞,曹继刚,舒劲松.补肾毓麟汤对肾虚性生殖功能障碍大鼠生育力影响的实验研究[J].湖北中医学院学报,2005,7(3):7-9. 被引量:7
  • 2蔡光先,刘柏炎,陈奕安.六味地黄汤对宫内发育迟缓胎鼠脑发育的影响[J].中华中医药杂志,2007,22(9):642-644. 被引量:12
  • 3Alexandra Scholze,Ying Liu,Lise Pedersen,Shengqiang Xia,Heinz J. Roth,Berthold Hocher,Lars Melholt Rasmussen,Martin Tepel.Soluble α-Klotho and Its Relation to Kidney Function and Fibroblast Growth Factor-23[J]. The Journal of Clinical Endocrinology & Metabolism . 2014 (5)
  • 4Yuhong Wang,Zhongjie Sun.Current understanding of klotho[J]. Ageing Research Reviews . 2008 (1)
  • 5Yorito Anamizu,Hiroshi Kawaguchi,Atsushi Seichi,Shinji Yamaguchi,Emiko Kawakami,Naotoshi Kanda,Shiro Matsubara,Makoto Kuro-o,Yoichi Nabeshima,Kozo Nakamura,Kiyomitsu Oyanagi.Klotho insufficiency causes decrease of ribosomal RNA gene transcription activity, cytoplasmic RNA and rough ER in the spinal anterior horn cells[J]. Acta Neuropathologica . 2005 (5)
  • 6Mariko Kamemori,Yoshio Ohyama,Masahiko Kurabayashi,Katumasa Takahashi,Ryozo Nagai,Nobuhiko Furuya.Expression of Klotho protein in the inner ear[J]. Hearing Research . 2002 (1)
  • 7Lee EY,Kim SS,Lee JS,et al.Soluble alpha-klotho as a novel biomarker in the early stage of nephropathy in patients with type 2diabetes. PLoS One . 2014
  • 8Imura A.Updates on rickets and osteomalacia:various roles of Klotho and FGF23in vivo. Clinical Calcium . 2013
  • 9Liu ZH.Nephrology in China. Nat Rev Nephrol . 2013
  • 10Nagai Taku,Yamada Kiyofumi,Kim Hyoung-Chun,Kim Yong-Sun,Noda Yukihiro,Imura Akihiro,Nabeshima Yo-ichi,Nabeshima Toshitaka.Cognition impairment in the genetic model of aging klotho gene mutant mice: a role of oxidative stress. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology . 2002

共引文献64

同被引文献75

引证文献5

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部