摘要
目的观察甲磺酸倍他司汀联合手法复位治疗良性阵发性位置性眩晕(BPPV)的疗效。方法选取2017年1月至2019年11月期间我院收治的147例BPPV患者,采用抽签方式随机分为对照组(n=73)和观察组(n=74)。对照组予相应手法复位治疗,观察组予口服甲磺酸倍他司汀联合手法复位治疗。治疗1周后观察两组的疗效,并对比两组眩晕障碍量表(DHI)、Berg平衡量表(BBS)评分以及前庭症状指数(VSI)的改善情况,并随访6个月,统计其复发情况。结果治疗前,两组患者的DHI评分、BBS评分以及VSI指数无明显差异(P>0.05);治疗后,两组患者的DHI、BBS评分以及VSI指数均有所改善(P<0.05),且观察组的DHI评分和VSI指数低于对照组,BBS评分则高于对照组,组间差异显著(P<0.05)。随访6个月,对照组和观察组的复发率分别为26.39%(19/72)、6.94%(5/72),观察组低于对照组,两组相比差异显著(P<0.05),观察组的总有效率为94.44%,而对照组总有效率为81.94%,两组比较差异有统计学意义(P<0.05)。结论BPPV患者采用甲磺酸倍他司汀联合手法复位治疗,疗效显著,复发率低,值得临床推广。
Objective To investigate the effect of betastinemesylate combined with manual reduction on benign paroxysmal positional vertigo(BPPV).Methods From January 2017 to November 2019,147 patients were randomly divided into control group(n=73)and observation group(n=74).The patients in the control group were treated with manual reduction according to their condition,while in the observation group were treated with Betastinemesylate combined with manual reduction.The clinical effect of the two groups was observed after 1 week of treatment,and the improvement of vertigo disorder scale(DHI),berg balance scale(BBS)score and vestibular symptom index(VSI)were compared between the two groups,and the recurrence was counted after 6 months follow-up.Results The total effective rate of the observation group was 94.44%compared to the control group of 81.94%(P<0.05).There was no significant difference in DHI score,BBS score and VSI index between the two groups before treatment(P>0.05).The DHI score,BBS score and VSI index of the two groups were improved after treatment(P<0.05),and the DHI score and VSI index of the observation group were lower than that of the control group,and the BBS score was higher than that of the control group,and the difference between the two groups was significant(P<0.05).After 6 months follow-up,the recurrence rate of control group and observation group was 26.39%(19/72)and 6.94%(5/72),respectively.The observation group was lower than control group,and the difference between the two groups was significant(P<0.05).Conclusion BPPV patients treated with Betastinemesylate combined with manual reduction can improve the curative effect,further improve the symptoms of vertigo,and help to control recurrence.Therefore this combination treatment is worth of clinical promotion.
作者
丁丹
Ding Dan(Department of Otorhinolaryngology,Head and Neck Surgery,Affiliated Hospital of Zunyi Medical University,Zunyi Guizhou 563099,China)
出处
《遵义医科大学学报》
2021年第6期775-778,共4页
Journal of Zunyi Medical University
