摘要
目的:探讨“病友辅导”干预法对首发精神分裂症患者的精神症状、自知力、服药依从性的影响。方法:选取2020年6月至2021年2月在赣州市第三人民医院住院的首发精神分裂症患者107例,用随机数字表法分为对照组(53例)和研究组(54例),对照组予以常规治疗,研究组加以“病友辅导”干预;选用阳性与阴性症状量表(PANSS)、自知力与治疗态度问卷(ITAQ)、服药依从性量表(MARS)、不良反应症状量表(TESS)作为测评工具,在干预前、干预2周末、4周末、6周末、8周末进行评定,分析比较各指标组间差异。结果:(1)研究组实际完成45例,对照组实际完成47例。(2)PANSS评分干预前后存在时间效应(F_(时间)=16.95,P<0.01),2周末两组间存在显著性差异(t=3.17,P<0.01)。(3)ITAQ评分干预前后存在时间效应(F_(时间)=23.29,P<0.01)、分组效应(F_(分组)=11.73,P<0.01)、交互效应(F_(交互)=32.81,P<0.01),2周末、4周末、6周末、8周末两组间差异均有统计学意义(P<0.01)。(4)MARS评分干预前后存在时间效应(F_(时间)=37.73,P<0.01)、分组效应(F_(分组)=14.25,P<0.01)、交互效应(F_(交互)=20.16,P<0.01),2周末、4周末、6周末、8周末两组间差异均有统计学意义(P<0.01)。结论:“病友辅导”干预法对首发精神分裂症患者早期治疗阶段症状改善具有快速起效的辅助作用,在8周的干预期间能持续提升自知力水平、增强服药依从性,初步获得较好的临床效果。
Objective:To explore the effects of"coaching patients"intervention on symptom improvement,insight and medication compliance of first-episode schizophrenics.Methods:The patients with first-episode schizophrenia hospital‐ized in the Third People's Hospital of Ganzhou from June 2020 to February 2021 were selected.They were randomly di‐vided into control group(53 cases)and study group(54 cases).The control group was given routine treatment and the study group was given"coaching patients"intervention on the basis of routine treatment.Positive and Negative Symptom Scale(PANSS),Insight and Treatment Attitude Questionnaire(ITAQ),Medication Adherence Rating Scale(MARS)and Treatment Emergent Symptom Scale(TESS)were used as evaluation tools.The differences between the two groups at each time point were evaluated,including before intervention,at the end of 2,4,6 and 8 weeks after intervention.Re⁃sults:(1)The actual completions were 45 cases in the study group and 47 cases in the control group.(2)PANSS score had time effect before and after intervention(F_(time)=16.95,P<0.01),and there was significant difference between the two groups at the end of 2 weeks(t=3.17,P<0.01).(3)ITAQ score had were time effect(F_(time)=23.29,P<0.01),grouping effect(F_(grouping)=11.73,P<0.01)and interaction effect(F_(interaction)=32.81,P<0.01)before and after ITAQ score intervention.There were significant differences between the two groups at the end of 2,4,6 and 8 weeks,with statistical significance(P<0.01).(4)MARS score had time effect(F_(time)=37.73,P<0.01),grouping effect(F_(grouping)=14.25,P<0.01)and interaction effect(F_(interaction)=20.16,P<0.01)before and after intervention.There were significant differences between the two groups at the end of 2,4,6 and 8 weeks(P<0.01).Conclusion:"Coaching patients"intervention has a rapid and effective auxiliary effect on symptom improvement in the early treatment stage,During the 8-week inter‐vention period,it can continuously improve the level of insight and enhance medication compliance,and initially obtain good clinical results.
作者
苏建宁
陈年梅
谢秀东
李杨
黄丽
陈吉祥
张杨正浩
SU Jian-ning;CHEN Nian-mei;XIE Xiu-dong;LI Yang;HUANG Li;CHEN Ji-xiang;ZHANGYANG Zheng-hao(The Third People's Hospital of Ganzhou,Ganzhou,Jiangxi 341000)
出处
《赣南医学院学报》
2021年第12期1211-1215,共5页
JOURNAL OF GANNAN MEDICAL UNIVERSITY
基金
江西省卫生健康委员会科技计划项目(202140669)。
关键词
病友辅导
首发精神分裂症
疗效
自知力
依从性
Coaching patients
First-episode schizophrenia
Curative effect
Insight
Compliance
