摘要
目的分析体外循环下切除侵犯心脏大血管的T4ⅢA期非小细胞肺癌的疗效。探讨体外循环在此类手术中的应用经验。方法回顾性分析2006至2015年在空军军医大学附属医院完成的16例体外循环下肺癌扩大切除术患者的临床资料与5年随访结果。全部手术通过股动脉、股静脉转流建立体外循环,正中开胸完成肺癌组织切除与缺损心血管组织重建。结果本组病例均顺利完成肺癌扩大切除术,无围术期死亡。平均体外循环时间(67.1±27.9)min,平均升主动脉阻闭时间(39.3±12.3)min。术后1年随访肿瘤复发2例(12.5%),5年随访显示肿瘤复发4例(25.0%)。结论体外循环下扩大切除侵犯心脏大血管的T4ⅢA期非小细胞肺癌安全,近期及远期效果良好。但此类手术的体外循环技术有其自身特点,应予以重视。
Objective To analyze the efficacy of cardiopulmonary bypass(CPB)in patients with T4 stageⅢA non-small cell lung cancer invading the heart and great blood vessels,and to explore the application experience of CPB in this kind of surgery.Meth⁃ods The clinical data and 5-year follow-up results of 16 patients who underwent extensive resection of lung cancer under CPB in the First Affiliated Hospital and the Second Affiliated Hospital of Air Force Military Medical University from 2006 to 2015 were analyzed retrospectively.All operations established CPB through femoral artery and femoral vein bypass,and extended lung cancer tissue resec⁃tion and defect cardiovascular tissue reconstruction were performed through median thoracotomy.Results All cases successfully com⁃pleted extended resection of lung cancer without perioperative death.The mean CPB time was(67.1±27.9)min and the mean aortic cross-clamp time was(39.3±12.3)min.Tumor recurrence occurred in 2 cases(12.5%)after 1 year follow-up and 4 cases(25.0%)after 5 years follow-up.Conclusion Extended resection of T4 stageⅢA non-small cell lung cancer with cardiac vascular invasion under CPB is safe and has good short-term and long-term results.However,the CPB technology of this kind for operation has its own characteristics,and the surgeons should pay attention to them.
作者
梁宏亮
李子林
董小超
金振晓
刘金成
魏巍
陈涛
Liang Hongliang;Li Zilin;Dong Xiaochao;Jin Zhenxiao;Liu Jincheng;Wei Wei;Chen Tao(Department of Cardiovascular Surgery,Xijing Hospital,Air Force Military Medical University,Shaan'xi Xi'an 710032,China)
出处
《中国体外循环杂志》
2021年第6期347-350,共4页
Chinese Journal of Extracorporeal Circulation
基金
陕西省创新人才推进计划(2017KJXX-05)。
关键词
非小细胞肺癌
扩大切除
体外循环
Non-small cell lung cancer
Extended resection
Cardiopulmonary bypass
