摘要
目的观察清热祛湿化浊汤口服联合痔炎冲洗散熏洗治疗湿热下注型慢性肛窦炎的临床疗效。方法将181例湿热下注型慢性肛窦炎患者按照随机数字表法分为4组,复方角菜酸酯栓组45例予复方角菜酸酯栓纳肛治疗,清热祛湿化浊汤组45例予清热祛湿化浊汤口服治疗,痔炎冲洗散熏洗组45例予痔炎冲洗散熏洗治疗,联合组46例予清热祛湿化浊汤口服联合痔炎冲洗散熏洗治疗。4组均治疗14 d,治疗后随访3个月。比较4组疗效;观察4组治疗前后中医症状评分变化;观察4组复发情况、不良反应发生情况。结果复方角菜酸酯栓组总有效率66.67%(30/45),痔炎冲洗散熏洗组总有效率77.78%(35/45),清热祛湿化浊汤组总有效率80.00%(36/45),联合组总有效率95.65%(44/46),联合组总有效率高于复方角菜酸酯栓组、痔炎冲洗散熏洗组、清热祛湿化浊汤口服组(P<0.05)。4组治疗后主症、次症、舌脉评分及总评分均较本组治疗前降低(P<0.05);痔炎冲洗散熏洗组、清热祛湿化浊汤口服组、联合组治疗后主症、次症、舌脉评分及总评分均低于复方角菜酸酯栓组(P<0.05);联合组治疗后主症、次症、舌脉评分及总评分低于痔炎冲洗散熏洗组、清热祛湿化浊汤口服组(P<0.05)。复方角菜酸酯栓组复发率33.33%(5/15),痔炎冲洗散熏洗组复发率22.22%(4/18),清热祛湿化浊汤组复发率25.00%(4/16),联合组复发0例,联合组复发率低于复方角菜酸酯栓组、痔炎冲洗散熏洗组、清热祛湿化浊汤组(P<0.05)。4组不良反应发生率比较差异均无统计学意义(P>0.05)。结论清热祛湿化浊汤口服联合痔炎冲洗散熏洗治疗湿热下注型慢性肛窦炎,可缓解患者临床症状,提高临床疗效,降低复发,安全性好。
Objective To explore the clinical observation of fumigation-washing therapy of Hemorrhoids Washing Powder(HWP)combined with oral administration of Qingre Qushi Huazhuo Decoction(QQHD)on chronic anal cryptitis of damp-heat type.Methods Totally 181 patients with chronic anal cryptitis(damp-heat type)were grouped as random number table,four groups were treated for 14 days and followed up for 3 months.Efficacy analysis was performed on the four groups which comprised 45(Western medicine group),45(HWP group),45(QQHD group),and 46(combined group)patients.The key observation was the changes of traditional Chinese medicine(TCM)symptom scores,recurrence rate,adverse incidence between groups before and after treatment.Results The total effective rates in Western medicine group,HWP group,QQHD group,combined group were 66.67%(30/45),77.78%(35/45),80.00%(36/45)and 95.65%(44/46),respectively,the curative effect being better in combined group than the other groups(P<0.05).After treatment,the scores of main symptoms,sub-symptoms,vessels of tongue in groups were decreased,which in the comparison of the four,HWP group,QQHD group and combined group were lower than Western medicine group(P<0.05),and combined group was lower than HWP group and QQHD group(P<0.05).The recurrence rate in combined group was lower than that in Western medicine group,HWP group,QQHD group[0 vs 33.33%(5/15),0 vs 22.22%(4/18),0 vs 25.00%(4/16),(P<0.05),respectively],the difference was not statistically significant in the adverse incidence among four groups(P>0.05).Conclusion For patients with chronic anal sinusitis(damp-heat type),the combination of the above two can significantly relieve clinical symptoms,which is capable of inhibiting inflammatory reaction,improving clinical efficacy and reducing recurrence rate,with good safety.
作者
魏妮
孙林梅
苏红波
孙兴伟
唐林
WEI Ni;SUN Linmei;SU Hongbo;SUN Xingwei;TANG Lin(Department of Anorectal,Xi'an Hospital of Traditional Chinese Medicine,Xi'an,Shaanxi 710021;不详)
出处
《河北中医》
2021年第11期1836-1839,共4页
Hebei Journal of Traditional Chinese Medicine
关键词
肛门疾病
慢性病
中医疗法
Anus disease
Chronic disease
Traditional Chinese medicine therapy
