摘要
扩散加权成像(diffusion weighted imaging,DWI)技术无需对比剂即可获得组织的水分子扩散情况。然而单指数DWI无法区分组织内单纯水分子扩散和微循环灌注信息,体素内不相干运动扩散加权成像(intravoxel incoherent motion-diffusion weighted imaging,IVIM-DWI)通过双指数曲线拟合,可以分别获得单纯水分子扩散和微循环灌注参数,能够更全面、准确地反映肿瘤组织微观结构的复杂性。近年来,IVIM-DWI在肺部的应用研究逐渐增多,已成为肺功能磁共振成像研究的热点。笔者就肺部IVIM-DWI相关技术参数、IVIM-DWI对肺良恶性病变的鉴别及其在肺癌评估中的应用进展进行综述。
The diffusion weighted imaging(DWI)can reflect the degree of diffusion of water molecules in tissues without contrast enhancement.However,DWI is a mono-exponential model,which cannot separate the pseudo-diffusion from pure molecular diffusion.Intravoxel incoherent motion diffusion-weighted imaging(IVIM-DWI)utilizes a double-exponential model to obtain parameters of pure water molecule diffusion and microcirculatory perfusion-related diffusion,more comprehensively and accurately reflects the complexity of the microstructure of the tumor tissue.In recent years,the application of IVIM-DWI in lung has been gradually increasing and become the focus of lung functional magnetic resonance imaging research.In this paper,we mainly reviewed the technical parameters of IVIM-DWI in lung and related research progress in the diagnosis and treatment of the lung cancer.
作者
吕四强
秦文恒
孙占国
LÜ Siqiang;QIN Wenheng;SUN Zhanguo(Clinical Medical College of Jining Medical University,Jining 272013,China;Department of Medical Imaging,Affiliated Hospital of Jining Medical University,Jining 272029,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2022年第2期141-144,共4页
Chinese Journal of Magnetic Resonance Imaging
基金
山东省医药卫生科技发展计划项目(编号:202009011151)
济宁医学院附属医院“苗圃”科研计划项目(编号:MP-ZD-2020-003)。
关键词
肺癌
体素内不相干运动
磁共振成像
扩散加权成像
lung cancer
intravoxel incoherent motion
magnetic resonance imaging
diffusion weighted imaging
