摘要
瘀毒致病是阐释慢性萎缩性胃炎(CAG)发生、发展的重要理论,认为瘀血、湿浊、湿热蕴结,久化瘀毒、浊毒,裹挟留滞,终成热毒,隐匿为害,导致本病迁延难愈。此外,焦虑、抑郁状态(郁)亦是CAG发生、发展的危险因素。探讨瘀、毒、郁的内涵以及三者在CAG中的致病机制,并通过辨析瘀与毒、郁与瘀、毒与郁之间的关系,认为“瘀、毒、郁”互结是CAG的核心病机,其中“郁”可能是促进瘀血、湿浊、湿热转为瘀毒、浊毒,进而化生热毒的病理要素。
The theory of“stasis and toxins leading to diseases”which is widely used in explaining the evolving process of chronic atrophic gastritis(CAG),holds that the long-term accumulation and binding of blood stasis,dampturbidity and damp-heat may evolve into stasis toxin and turbidity toxin,which can further develop into heat toxin.Due to the concealed conduction,the disease is protracted and refractory.Additionally,anxiety and depression(con⁃straints)are also the risk factors for the occurrence and development of CAG.By exploring the connotation of stasis,toxins and constraints and their pathogenic mechanism in CAG,and by distinguishing the relationships of stasistoxins,constraints-stasis,and toxins-constraints,it is considered that the binding of stasis,toxins and constraints should be the core pathogenesis of CAG,and“constraints”is the pathological factor to promote the development of stasis toxin and turbidity toxin from blood stasis,damp-turbidity and damp-heat,and then transform into heat toxin.
作者
张泰
张北华
马祥雪
王凤云
王萍
唐旭东
ZHANG Tai;ZHANG Beihua;MA Xiangxue;WANG Fengyun;WANG Ping;TANG Xudong(Graduate School,China Academy of Chinese Medical Sciences,Beijing,100700;Xiyuan Hospital,China Academy of Chinese Medical Sciences;China Academy of Chinese Medical Sciences)
出处
《中医杂志》
CSCD
北大核心
2022年第3期229-233,共5页
Journal of Traditional Chinese Medicine
基金
国家中医药传承创新团队项目(ZYYCXTD-C-202010)。
关键词
慢性萎缩性胃炎
瘀
毒
郁
焦虑
抑郁
炎癌转化
chronic atrophic gastritis
stasis
toxins
constraint
anxiety
depression
inflammation-cancer transfor⁃mation
