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高血压家族史和行为危险因素聚集与高血压患病关系 被引量:19

Associations of family hypertension history and clustered behavioral risk factors with hypertension among community adult residents in Nantong city
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摘要 目的了解高血压家族史和行为危险因素聚集与高血压患病的关系,为制定适宜的高血压防治策略提供参考依据。方法于2018年10—11月采用分层随机整群抽样方法在江苏省南通市崇川区抽取12092名≥18周岁常住居民进行问卷调查和体格检查,并采用多因素非条件logistic回归模型分析高血压家族史和行为危险因素聚集对高血压患病的影响。结果南通市崇川区最终纳入分析的12064名≥18周岁常住居民中,患高血压者4042例,高血压患病率为33.5%,标化患病率为27.0%。在调整了性别、年龄、文化程度、婚姻状况、职业和体质指数等混杂因素后,多因素非条件logistic回归分析结果显示,有高血压家族史者高血压患病风险为无高血压家族史者的2.05倍(OR=2.05,95%CI=1.77~2.38),饮酒者高血压患病风险为非饮酒者的2.04倍(OR=2.04,95%CI=1.32~3.17),高盐饮食者高血压患病风险为非高盐饮食者的1.92倍(OR=1.92,95%CI=1.19~3.07);当高血压家族史与1种行为危险因素聚集时以家族史与高盐饮食聚集者高血压患病的风险为最大(OR=3.38,95%CI=2.35~4.85),当高血压家族史与2种行为危险因素聚集时以家族史与吸烟和高盐饮食聚集者高血压患病的风险为最大(OR=5.42,95%CI=2.73~10.74),当高血压家族史与3种行为危险因素聚集时以家族史与吸烟、饮酒和高盐饮食聚集者高血压患病的风险为最大(OR=5.84,95%CI=2.74~12.43)。结论高血压家族史与行为危险因素聚集可导致高血压的患病风险上升。 Objective To explore associations of family hypertension history and behavioral risk factor aggregation with hypertension incidence among adult residents for providing evidences to the development of effective strategies on prevention and treatment of hypertension.Methods Using stratified random cluster sampling and the uniform questionnaire for national program on chronic disease prevention and control,we conducted face-to-face interviews and physical examinations among 12092 permanent residents aged 18 years and above in an urban district of Nantong city,Jiangsu province during October-November 2018.Multivariate logistic regression model was adopted in analysis on the effect of family hypertension history and clustered behavioral risk factors on hypertension incidence.Results Among the 12064 residents with complete information,totally 4042 hypertensives were identified,with the crude and standardized prevalence rate of 33.5%and 27.0%,respectively.After adjusting for confounding factors such as gender,age,education,marital status,occupation and body mass index,multivariate logistic regression analyses showed that the residents exposed to following factors had an increased risk of hypertension:family history of hypertension(odds ratio[OR]=2.05,95%confidence interval[95%CI]:1.77-2.38),alcohol-drinking(OR=2.04,95%CI:1.32-3.17),and consuming high salt diet(OR=1.92,95%CI:1.19-3.07)compared to those without the exposures;the analyses also revealed that the residents with family history of hypertension and one or more behavioral risk factors were at a much higher risk of hypertension,with the ORs of 3.38(95%CI:2.35-4.85)for those with family hypertension history and consuming high salt diet,5.42(95%CI:2.73-10.74)for those with the history and smoking plus consuming high salt diet,and 5.84(95%CI:2.74-12.43)for those with the history and smoking plus alcohol drinking and consuming high salt diet,respectively.Conclusion Family history of hypertension and aggregation of behavioral risk factors can increase the risk of hypertension among adult community residents.
作者 段晓阳 李敏 祁志刚 曹雨馨 黄昊 葛启伟 郑会燕 秦刚 庄勋 DUAN Xiao-yang;LI Min;QI Zhi-gang(Department of Epidemiology and Health Statistics,School of Public Health,Nantong University,Nantong,Jiangsu Province 226019,China;不详)
出处 《中国公共卫生》 CSCD 北大核心 2022年第2期172-176,共5页 Chinese Journal of Public Health
关键词 高血压 患病 高血压家族史 行为危险因素 聚集 关系 hypertension prevalence family hypertension history behavioral risk factor clustering relationship
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