From Molecular Pathology of COVID-19 to Nigella Sativum as a Treatment Option:Scientific Based Evidence of Its Myth or Reality
摘要
COVID-19 virus is a causative agent of viral pandemic in human beings which specifically targets respiratory system of humans and causes viral pneumonia.This unusual viral pneumonia is rapidly spreading to all parts of the world,currently affecting about 105 million people with 2.3 million deaths.Current review described history,genomic characteristics,replication,and pathogenesis of COVID-19 with special emphasis on Nigella sativum(N.sativum)as a treatment option.N.sativum seeds are historically and religiously used over the centuries,both for prevention and treatment of different diseases.This review summarizes the potential role of N.sativum seeds against COVID-19 infection at levels of in silico,cell lines and animal models.
参考文献8
-
1吕新军(编译),Huang C,Wang Y,Li X.武汉市新型冠状病毒感染患者的临床特征[J].中华实验和临床病毒学杂志,2020,34(1):42-42. 被引量:2547
-
2ZHONG Nan-shan,YANG Zi-feng,JIANG Mei,LIANG Jing-yi.A Potential Chinese Medicine Granule Suppressing ARDS of COVID-19: Keguan-1[J].Chinese Journal of Integrative Medicine,2020,26(11):803-804. 被引量:5
-
3张益编(译).新型冠状病毒基因组与流行病学研究:病毒起源与受体结合的线索[J].中华预防医学杂志,2020,54(3):244-244. 被引量:520
-
4Yan-Rong Guo,Qing-Dong Cao,Zhong-Si Hong,Yuan-Yang Tan,Shou-Deng Chen,Hong-Jun Jin,Kai-Sen Tan,De-Yun Wang,Yan Yan.The origin, transmission and clinical therapies on coronavirus disease 2019(COVID-19) outbreak——an update on the status[J].Military Medical Research,2020,7(1):93-103. 被引量:153
-
5CHEN Yuan-bin,LIU Qiao,XIE Han,YIN Shuo-miao,WU Lei,YU Xu-hua,FAN Long,LIN Lin.Is Chinese Medicine Injection Applicable for Treating Acute Lung Injury and Acute Respiratory Distress Syndrome?A Systematic Review and Meta-analysis of Randomized Controlled Trials[J].Chinese Journal of Integrative Medicine,2020,26(11):857-866. 被引量:10
-
6LUO Hui,TANG Qiao-ling,SHANG Ya-xi,LIANG Shi-bing,YANG Ming,Nicola Robinson,LIU Jian-ping.Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs[J].Chinese Journal of Integrative Medicine,2020,26(4):243-250. 被引量:78
-
7WANG Jia-bo,WANG Zhong-xia,JING Jing,ZHAO Peng,DONG Jing-hui,ZHOU Yong-feng,YANG Guang,NIU Ming,ZHAO Xu,JIANG Tian-jun,Bl Jing-feng,XU Zhe,ZHANG Ping,WU Dan,BAI Zhao-fang,GUO Yu-ming,YU Si-miao,SUN Yong-qiang,ZHANG Zi-teng,ZHAN Xiao-yan,LI Peng-yan,DING Jin-biao,ZHAO Peng-fei,SONG Xue-ai,TANG Jian-yuan,HE Dong-chu,CHEN Zhu,QIN En-qiang,WANG Rui-lin,XIAO Xiao-he.Exploring an Integrative Therapy for Treating COVID-19:A Randomized Controlled Trial[J].Chinese Journal of Integrative Medicine,2020,26(9):648-655. 被引量:22
-
8Aftab Ahmad,Asif Husain,Mohd Mujeeb,Shah Alam Khan,Abul Kalam Najmi,Nasir Ali Siddique,Zoheir A.Damanhouri,Firoz Anwar.A review on therapeutic potential of Nigella sativa:A miracle herb[J].Asian Pacific Journal of Tropical Biomedicine,2013,3(5):337-352. 被引量:19
二级参考文献62
-
1王旭东,李明,张超,杜波,韩大贺.血必净治疗ARDS疗效及其对炎症相关细胞因子的影响[J].徐州医学院学报,2007,27(11):732-735. 被引量:10
-
2Sherif S. Mahmoud,Vladmir P. Torchilin.Hormetic/Cytotoxic Effects of Nigella sativa Seed Alcoholic and Aqueous Extracts on MCF-7 Breast Cancer Cells Alone or in Combination with Doxorubicin[J]. Cell Biochemistry and Biophysics . 2013 (3)
-
3Xiaofei Lei,Meng Liu,Zirong Yang,Mengyao Ji,Xufeng Guo,Weiguo Dong.Thymoquinone Prevents and Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice[J]. Digestive Diseases and Sciences . 2012 (9)
-
4Ahmad Nazrun Shuid,Norazlina Mohamed,Isa Naina Mohamed,Faizah Othman,Farihah Suhaimi,Elvy Suhana Mohd Ramli,Norliza Muhammad,Ima Nirwana Soelaiman,Srijit Das.Nigella sativa : A Potential Antiosteoporotic Agent[J]. <journal-title>Evidence-Based Complementary and Alternative Medicine . 2012
-
5Cuneyt Tayman,Ferhat Cekmez,Ilker Mustafa Kafa,Fuat Emre Canpolat,Merih Cetinkaya,Sema Uysal,Turan Tunc,S.Umit Sar?c?.Beneficial Effects of Nigella Sativa Oil on Intestinal Damage in Necrotizing Enterocolitis[J]. Journal of Investigative Surgery . 2012 (5)
-
6Neveen A. Noor,Heba S. Aboul Ezz,Abdel Razik Faraag,Yasser A. Khadrawy.Evaluation of the antiepileptic effect of curcumin and Nigella sativa oil in the pilocarpine model of epilepsy in comparison with valproate[J]. Epilepsy and Behavior . 2012 (2)
-
7Mahmoud-Awny Magdy,El-Abhar Hanan,El-Maraghy Nabila.Thymoquinone: Novel gastroprotective mechanisms[J]. European Journal of Pharmacology . 2012 (1-3)
-
8Sadiq Umar,Jamil Zargan,Khalid Umar,Sayeed Ahmad,Chandra Kant Katiyar,Haider A. Khan.Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats[J]. Chemico-Biological Interactions . 2012 (1)
-
9Bahaa K.A. Abel-Salam.Immunomodulatory effects of black seeds and garlic on alloxan-induced Diabetes in albino rat[J]. Allergologia et Immunopathologia . 2011 (6)
-
10Mohammad FarazZafeer,MohammadWaseem,ShaistaChaudhary,SuhelParvez.Cadmium‐induced hepatotoxicity and its abrogation by thymoquinone[J]. J. Biochem. Mol. Toxicol. . 2012 (5)
共引文献3181
-
1Parva Namiranian,Omid Sadatpour,Sadegh Azimzadeh Jamalkandi,Mohammad Hossein Ayati,Mehrdad Karimi.Antiviral Activity of Medicinal Plants against Human Coronavirus: a systematic scoping review of in vitro and in vivo experimentations[J].Journal of Traditional Chinese Medicine,2022,42(3):332-343.
-
2韩江余,贾芸,富徐燕,徐浩.中药防疫方对H1N1感染模型小鼠炎症因子与肺组织菌群的影响[J].中医外治杂志,2023,32(5):1-5.
-
3林春苗,秦彤,陆昱养,余乐熺.83例新型冠状病毒肺炎病例CT图像定量分析[J].预防医学,2021,33(6):568-572.
-
4林嘉荣,郑慰武,曾贵兴,林启展.金花清感颗粒治疗新型冠状病毒肺炎网络药理学的研究[J].中药材,2020,43(8):2070-2076. 被引量:13
-
5张泽鑫,吴汶丰,谢丹,方舒涵,李红毅.基于网络药理学和分子对接分析达原饮治疗新型冠状病毒肺炎(COVID-19)的分子靶点和机制[J].中药材,2020,43(8):2062-2069. 被引量:17
-
6许洪彬,李珮馨,綦向军,莫嘉浩,黄演芬,方彩珊,林丽珠.基于网络药理学和分子对接研究疏风解毒胶囊治疗新型冠状病毒肺炎的机制[J].中药材,2020,43(8):2053-2061. 被引量:3
-
7陈明骏,高路,仝战旗.基于肾素-血管紧张素系统筛选治疗新型冠状病毒肺炎有效中药的网络药理学研究[J].中药材,2020(5):1291-1296. 被引量:2
-
8王林,杨志华,张浩然,于航星,杨康,付宝慧,杨洪涛.连花清瘟治疗新型冠状病毒(2019-nCoV)肺炎网络药理学研究与初证[J].中药材,2020(3):772-778. 被引量:74
-
9LI Tong,YU Xing,CHEN Meng-xiang,LV Yuan,ZHA Wen-ting.Genomic Characteristics of SARS-CoV,MERS-CoV and 2019-nCoV[J].Chinese Journal of Biomedical Engineering(English Edition),2021,30(1):30-39. 被引量:1
-
10刘强,牛小霞,陈吉祥,加华才让,高辉,方敏,刘艳玲,张思浓,李勇.冠状病毒的反向遗传学研究进展[J].中国病原生物学杂志,2024,19(2):230-236. 被引量:1
-
1Qi Chen,Xing-Yao Huang,Ying Tian,Changfa Fan,Mengxu Sun,Chao Zhou,Ruiting Li,Rong-Rong Zhang,Guizhen Wu,Cheng-Feng Qin.The Infection and Pathogenicity of SARS-CoV-2 Variant B.1.351 in hACE2 Mice[J].Virologica Sinica,2021,36(5):1232-1235. 被引量:2
-
2马卫华,王春海.使用Veeam实现物理机到虚拟机迁移[J].网络安全和信息化,2021(10):102-106.
-
3王占军,王宪玲,宋旸,常红,李旭颖,王朝东,李存江.DYNC1H1基因突变导致以下肢受累为主的脊髓性肌萎缩症家系分析[J].北京医学,2021,43(5):388-392. 被引量:3
-
4Yuxi Zhao,Gu He,Wei Huang.A novel model of molnupiravir against SARS-CoV-2 replication: accumulated RNA mutations to induce error catastrophe[J].Signal Transduction and Targeted Therapy,2022,7(1):1-3.
-
5Immacolata Polvere,Serena Voccola,Gaetano Cardinale,Maurizio Fumi,Francesca Aquila,Alfredina Parrell,Jessica Raffaella Madera,Romania Stilo,Pasquale Vito,Tiziana Zotti.A peptide-based assay discriminates individual antibody response to SARS-CoV-2[J].Genes & Diseases,2022,9(1):275-281.
-
6Ayo O Omiyale.Solid pseudopapillary neoplasm of the pancreas[J].World Journal of Hepatology,2021,13(8):896-903. 被引量:10
-
7JEREMIAH JENNE.MYTH AND MECHAS[J].The World of Chinese,2021(6):80-82.
-
8Zihua Zhan,Runting Li.City Image Analysis of Food in Guangzhou-Taking Yamaha Fish Stall as an Example[J].Proceedings of Business and Economic Studies,2021,4(6):73-77.
-
9无.Medicine Labels[J].疯狂英语(初中天地),2022(2):49-50.
-
10Li Zhang,Rui Cao.Progress in target therapy of advanced non-small cell lung cancer[J].Drug Combination Therapy,2021,3(4):5-10.