摘要
本研究探究了数字减影CT灌注成像(SCTP)技术检测血流量(BF)、血容量(BV)、对比剂平均通过时间(MTT)对早期股骨头缺血性坏死(ANFH)的诊断价值及对预后的影响。以单侧ANFH患者66例作为研究对象,对患侧、健侧股骨头行SCTP技术检查,结果显示,患侧股骨头BF、BV明显低于健侧,MTT明显长于健侧(P<0.05);股骨头BF、BV、MTT诊断ANFH的AUC为0.866、0.755、0.820,三者联合诊断ANFH的AUC为0.911,敏感性为95.45%,特异性为83.33%,诊断价值高于单一诊断(P<0.05);随访1年,失访4例。62例患者中预后良好41例,预后不良21例。不同预后患者疾病分期、坏死体积、坏死部位、股骨头BF、BV、MTT差异有统计学意义(P<0.05);股骨头BF、BV与疾病分期、坏死体积呈负相关,MTT与疾病分期、坏死体积呈正相关(P<0.05);股骨头BF、BV、MTT是预后的重要影响因素(P<0.05)。SCTP检测股骨头BF、BV、MTT联合诊断早期ANFH价值可靠,可为临床预测、评估预后提供重要参考。
This study explored the diagnostic value of digital subtraction CT perfusion imaging(SCTP)technology in detecting blood flow(BF),blood volume(BV),and mean transit time(MTT)on early avascular necrosis of the femoral head(ANFH)and its impact on prognosis.Sixty-six patients with unilateral ANFH were taken as the research object.SCTP technique was performed on the femoral head of the affected and healthy side.The results showed that the BF and BV of the femoral head of the affected side were lower than that of the healthy side,and the MTT was longer than that of the healthy side(P<0.05).The AUC of bone BF,BV,and MTT to diagnose ANFH was 0.866,0.755,and 0.820.The AUC of the three combined diagnosis of ANFH was 0.911,the sensitivity was 95.45%,the specificity was 83.33%,and the diagnostic value was higher than that of a single diagnosis(P<0.05).Follow-up for 1 year,4 cases were lost to follow-up.Among the 62 patients,41 had a good prognosis and 21 had a poor prognosis.There were statistically significant differences in disease stage,necrotic volume,necrotic location,femoral head BF,BV,and MTT in patients with different prognosis(P<0.05).Femoral head BF and BV were negatively correlated with disease stage and necrotic volume,and MTT was correlated with disease stage,the volume of necrosis was positively correlated(P<0.05).Femoral head BF,BV,MTT were important prognostic factors(P<0.05).Therefore,the SCTP detection of femoral head BF,BV,and MTT has a reliable value in the early diagnosis of ANFH,and it can also provide an important reference for clinical prediction and prognosis assessment.
作者
张静
郭宁茹
菅夏楠
李丹丹
武亚芳
ZHANG Jing;GUO Ningru;JIAN Xianan;LI Dandan;WU Yafang(Puyang Medical College,Puyang 457000,Henan,P.R.China;Puyang Oilfield General Hospital,Puyang 457000,Henan,P.R.China)
出处
《影像科学与光化学》
CAS
北大核心
2022年第2期311-315,共5页
Imaging Science and Photochemistry
关键词
股骨头缺血性坏死
数字减影CT灌注成像
血流量
血容量
对比剂平均通过时间
avascular necrosis of the femoral head
digital subtraction CT perfusion imaging
blood flow
blood volume
mean transit time of contrast agent
