摘要
目的:分析急性心肌梗死(AMI)患者血清低密度脂蛋白胆固醇(LDL-C)、C反应蛋白(CRP)、脑钠肽(BNP)水平的变化与冠状动脉血管病变严重程度的关系。方法:选取接受经皮冠脉介入术(PCI)治疗的AMI患者88例,根据Gensini评分将患者分为轻度组、中度组和重度组,比较血清LDL-C、CRP、BNP水平。结果:3组患者血清LDL-C、CRP、BNP水平比较差异有统计学意义(P<0.05);Pearson相关分析表明,血清LDL-C、CRP、BNP水平与Gensini评分呈正相关;多因素Logistic回归分析结果表明,血清LDL-C、CRP、BNP水平均是冠状动脉血管病变严重程度的预测因素。结论:AMI患者血清LDL-C、CRP、BNP水平与冠状动脉血管病变严重程度密切相关,是AMI患者冠状动脉血管病变严重程度的预测因子。
Objective:To analyze the relationship between the changes of serum low density lipoprotein cholesterol(LDL-C),C-reactive protein(CRP),brain natriuretic peptide(BNP)levels and the severity of coronary artery disease in patients with acute myocardial infarction(AMI).Methods:A total of 88 patients with AMI who received percutaneous coronary intervention(PCI)were selected and divided into mild group,moderate group and severe group according to Gensini scores,and their serum LDL-C,CRP,and BNP levels were compared.Results:There were statistically significant differences in serum LDL-C,CRP,and BNP levels among the 3 groups(P<0.05).And Pearson correlation analysis showed that serum LDL-C,CRP,BNP levels were significantly positively correlated with Gensini scores;the results of multivariate Logistic regression analysis showed that serum LDL-C,CRP,and BNP levels were the predictors of the severity of coronary artery disease.Conclusion:Serum LDL-C,CRP,BNP levels in patients with AMI are closely related to the severity of coronary artery disease.It is a predictor of the severity of coronary vascular disease in patients with AMI.
作者
刘红霞
张建立
洪云飞
Liu Hongxia;Zhang Jianli;Hong Yunfei(Department of Cardiology,The Third People's Hospital of Yunnan Province,Kunming 650200,China)
出处
《大理大学学报》
2022年第2期46-50,共5页
Journal of Dali University
关键词
急性心肌梗死
低密度脂蛋白胆固醇
C反应蛋白
脑钠肽
GENSINI评分
acute myocardial infarction
low density lipoprotein cholesterol
C-reactive protein
brain natriuretic peptide
Gensini scores
