摘要
Gastroesophageal reflux disease(GERD)has a high prevalence worldwide.Li et al performed a well-designed study on the efficacy of modified Xiaochaihu decoction(MXD)for GERD,which showed that MXD is an optional therapy for GERD beyond proton pump inhibitors(PPIs).The herbal granule administration mode minimized the bias from traditional herbal formula in clinical trials.One limitation of that study was that it lacked records of side effects and rescue medication.As a chronic disease with recurrent symptoms,GERD rehabilitation requires prolonged observation of the clinical course with MXD therapy.
基金
Scientific Research Project of Zhejiang TCM Science and Technology Programme,No.2020ZB067,No.2020ZT001,and No.2021ZQ031
National Natural Science Foundation of China,No.81503522 and No.82104862.