摘要
目的探讨超声、钼靶及两者联合对高级别与中低级别乳腺导管原位癌(ductal carcinoma in situ,DCIS)的诊断价值。方法选取2015年1月至2020年12月于我院行乳腺手术、经病理确诊为DCIS且术前超声及钼靶影像资料完整的患者161例,共计196个病灶。以术后病理结果为金标准,将其分为高级别DCIS组80例和中低级别DCIS组116例。对两组的超声及钼靶表现进行对比分析。采用受试者工作特征(ROC)曲线下面积(AUC)分析超声与钼靶单独及联合诊断DCIS的价值。结果超声表现为微钙化在高级别DCIS组占比大,两组差异有统计学意义(P<0.01);肿块在中低级别DCIS组占比大,两组差异有统计学意义(P<0.01)。钼靶表现为微钙化在高级别DCIS组占比大,两组差异有统计学意义(P=0.026)。超声与钼靶单独及联合诊断DCIS的AUC分别为0.783、0.895、0.957。结论超声及钼靶表现为微钙化与高级别DCIS相关,超声表现为肿块与中低级别DCIS相关;超声与钼靶联合有助于诊断高级别与中低级别DCIS。
Objective To investigate the diagnostic value of ultrasonography,mammography and their combination in high-grade and middle-low-grade ductal carcinoma in situ(DCIS). Methods A total of 161 patients with 196 lesions who underwent ultrasound and mammography examination and confirmed by surgical pathology in our hospital between January 2015 and December 2020 were included. Taking pathological diagnosis as the gold standard,196 lesions were divided into high-grade DCIS group(n = 80)and middle-low-grade DCIS group(n = 116). The sonographic and mammographic features were analyzed and compared between the two groups. The area under curve(AUC)of the receiver operating characteristic(ROC)was used to analyze the diagnostic values of ultrasound and/or mammography for the DCIS. Results The percentage of microcalcification of sonography in the high-grade DCIS group was significantly higher than that in the middle-low-grade DCIS group(P < 0.01). The proportion of mass of sonography in the high-grade DCIS group was significantly lower than that in the middle-lowgrade DCIS group(P < 0.01). The proportion of microcalcification of mammography in the high-grade DCIS group was significantly higher than that in the middle-low-grade DCIS group(P = 0.026). The AUC of ultrasound and/or mammography for DCIS diagnosis were 0.783,0.895,and 0.957,respectively. Conclusion The ultrasonographic and mammographic features of microcalcification are correlated with high-grade DCIS and ultrasonographic features of mass are correlated with middle-low-grade DCIS. The combination of ultrasound and mammography can help to diagnostic both high-grade and middle-low-grade DCIS.
作者
武壮壮
张晓娟
史泽洪
史瑶
原韶玲
WU Zhuangzhuang;ZHANG Xiaojuan;SHI Zehong;SHI Yao;YUAN Shaoling(ShanXi Medical University,Taiyuan 030001,China;Department of Ultrasound,Affiliated Tumor Hospital of Shanxi Medical University,Taiyuan 030013,China;不详)
出处
《实用医学杂志》
CAS
北大核心
2022年第5期560-564,共5页
The Journal of Practical Medicine
关键词
乳腺导管原位癌
高级别
中低级别
超声
钼靶
ductal carcinoma in situ
high grade
middle-low grade
ultrasonography
mammography
