摘要
目的探讨绝经后T2DM患者VFA与BMD的相关性。方法回顾性分析研究169例采用生物电阻抗法测定VFA,MEDIX DR骨密度仪测定BMD值的绝经后T2DM患者,记录一般临床资料,检测生化指标及骨代谢指标等,采用椎体骨折风险评分模型进行风险评估。SPSS26.0软件进行统计学分析。结果(1)T2DM伴骨质疏松组在年龄、糖尿病病程、VFA、HbAlc、FPG高于T2DM伴骨量正常组,25羟维生素D、PINP、OC低于T2DM伴骨量正常组(P<0.05);(2)相关性分析显示,腰椎BMD与年龄、病程、FPG、VFA呈负相关(P<0.05);(3)多元线性回归分析显示,VFA与BMD呈负相关(P<0.05)。结论绝经后T2DM患者的VFA与腰椎BMD有关,随着VFA的增加会引起BMD下降。
Objective To investigate the correlation between VFA and BMD in postmenopausal T2 DM patients.Methods 169 postmenopausal T2 DM patients with VFA measured by bioelectrical impedance and BMD measured by DEXA were analyzed retrospectively.The general clinical data,biochemical indexes and bone metabolism indexes were recorded.The risk assessment was carried out by vertebral fracture risk score model.SPSS26.0 software was used for statistical analysis.Results(1)The age,duration of diabetes,VFA,HbAlc and FPG in the T2 DM group with osteoporosis were higher than those in the normal group with T2 DM and bone mass.25(OH)D,PINP and OC were lower than those in the normal group with normal bone mass(P<0.05).(2)Correlation analysis showed that lumbar BMD was negatively correlated with age,course of disease,FPG and VFA(P<0.05);(3)Multiple linear regression analysis showed that VFA was negatively correlated with BMD(P<0.05).Conclusion VFA in postmenopausal T2 DM patients is related to lumbar BMD.With the increase of VFA,BMD will decrease.
作者
张苑
魏枫
程冉
张悦
马瑞婷
朱丽
周坤
ZHANG Yuan;WEI Feng;CHENG Ran;ZHANG Yue;MA Rui-ting;ZHU Li;ZHOU Kun(Department of Endocrinology and metabolism,the First Affiliated Hospital of Baotou Medical College,Inner Mongolia University of science and technology,Baotou 014010 China)
出处
《内蒙古医学杂志》
2022年第3期259-261,共3页
Inner Mongolia Medical Journal
关键词
2型糖尿病
骨质疏松
骨密度
内脏脂肪
绝经后女性
type 2 diabetes mellitus
osteoporosis
bone mineral density
visceral fat
postmenopausal women
