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大柴胡汤加味治疗脑病后肺部多重耐药菌感染痰热腑实证的治疗价值研究

Therapeutic Value of Modified Dachaihu Decoction in the Treatment of Phlegm-heat Fu-organs after Encephalopathy
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摘要 目的探讨对脑病后肺部多重耐药菌感染痰热腑实证患者采用大柴胡汤加味方法进行治疗后获得临床效果。方法选取2018年1月—2020年12月收治的68例脑病后肺部多重耐药菌感染痰热腑实证患者进行治疗研究,随机分为参照组(采用营养神经及抗感染等系列西医常规疗法进行治疗)和研究组(在参照组治疗基础上,添加大柴胡汤加味方法进行治疗),各34例。比较两组患者治疗总有效率、肺部感染积分、证候积分(咳痰量、大便、痰色与质)。结果研究组治疗总有效率(94.12%)高于参照组(64.71%),差异有统计学意义(χ^(2)=8.994,P<0.05)。治疗前,研究组肺部感染积分(1.66±0.49)分同参照组肺部感染积分(1.69±0.52)分比较,差异无统计学意义(t=0.244,P>0.05);治疗后,研究组肺部感染积分(0.99±0.27)分低于参照组肺部感染积分(1.22±0.49)分,差异有统计学意义(t=2.397,P<0.05)。治疗前,研究组咳痰量(2.59±0.49)分、大便(2.95±0.31)分、痰色与质(2.79±0.37)分同参照组咳痰量(2.62±0.53)分、大便(2.97±0.38)分、痰色与质(2.82±0.39)分比较,差异无统计学意义(t=0.242、0.237、0.325,P>0.05);治疗后,研究组咳痰量(1.41±0.52)分、大便(1.39±0.51)分、痰色与质(1.49±0.39)分低于参照组咳痰量(1.89±0.79)分、大便(1.92±0.79)分、痰色与质(1.79±0.65)分,差异有统计学意义(t=2.959、3.286、2.307,P<0.05)。结论大柴胡汤加味方法治疗脑病后肺部多重耐药菌感染痰热腑实证,患者治疗总有效率提高,肺部感染积分、证候积分均获得显著改善,可促进总体治疗水平、预后水平显著提升。 Objective To explore the clinical effects of Dachaihu Decoction for patients with phlegm-heat fu organs infected by multi-drug resistant bacteria after encephalopathy.Methods A total of 68 patients with phlegm-heat and phlegm-heat infection in the lungs after encephalopathy from January 2018 to December 2020 were selected for treatment research.They were randomly divided into a reference group(treated with a series of conventional Western medicine therapies such as nutritional nerve and anti-infection)and a study group(based on the treatment of the reference group,with the addition of Dachaihu Decoction for treatment),with 34 cases in each group.The total effective rate of treatment,pulmonary infection score,and symptom score(volume of sputum,stool,sputum color and quality)were compared between the two groups.Results The total effective rate of treatment in the study group(94.12%)was higher than that in the reference group(64.71%),and the difference was statistically significant(χ^(2)=8.994,P<0.05).Before treatment,the lung infection score of the study group(1.66±0.49)points was compared with that of the reference group(1.69±0.52)points,and the difference was not statistically significant(t=0.244,P>0.05).After treatment,the lung infection score(0.99±0.27)points of the study group was lower than the lung infection score of the reference group(1.22±0.49)points,and the difference was statistically significant(t=2.397,P<0.05).Before treatment,the study group's sputum volume(2.59±0.49)points,stool(2.95±0.31)points,sputum color and quality(2.79±0.37)points were the same as those in the reference group(2.62±0.53)points,stool(2.97±0.38)points,sputum color and quality(2.82±0.39)points,and the difference was not statistically significant(t=0.242,0.237,0.325,P>0.05).After treatment,the study group's sputum volume(1.41±0.52)points,stool(1.39±0.51)points,sputum color and quality(1.49±0.39)points were lower than those of the reference group(1.89±0.79)points,stool(1.92±0.79)points,sputum color and quality(1.79±0.65)points,and the difference was statistically significant(t=2.959,3.286,2.307,P<0.05).Conclusion After the effective application of Dachaihu Decoction of patients with phlegm-heat fu-organ infections after encephalopathy,the total effective rate of treatment,pulmonary infection score and symptom score have been significantly improved.It can promote the overall treatment and prognosis.
作者 王晓磊 WANG Xiaolei(Department of Critical Care Medicine,Yantai Hospital of Traditional Chinese Medicine,Yantai,Shandong Province,264000 China)
出处 《系统医学》 2022年第3期45-48,共4页 Systems Medicine
关键词 脑病后肺部多重耐药菌感染痰热腑实证 大柴胡汤加味 治疗总有效率 肺部感染积分 证候积分 Pulmonary multi-drug-resistant bacteria infection after encephalopathy with phlegm-heat fu-organs Dachaihu Decoction plus flavor Total effective rate of treatment Pulmonary infection score Symptom score
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