摘要
目的分析双侧甲状腺切除术应用到甲状腺癌中,对患者炎症因子、生活质量、相关激素水平等指标的影响。方法选取2019年7月—2020年9月该院收治的86例甲状腺癌患者为研究对象,按照治疗方案不同分成对照组(单侧腺叶+峡部切除术)和双侧甲状腺切除组(双侧甲状腺全部切除术),各43例,对比两组应激相关激素水平、生活质量、疗效和炎症因子。结果两组患者术后FT4、TT4、FT3、TT3比较,差异无统计学意义(t=0.533、0.000、0.442、0.216,P>0.05);术后,双侧甲状腺切除组Cor、ACTH、NE较对照组低,差异有统计学意义(t=109.101、84.654、243.167,P<0.05);术后,双侧甲状腺切除组患者生活质量SF-36评分高于对照组,差异有统计学意义(P<0.0.5);术后,双侧甲状腺切除组IL-6、CRP较对照组低,差异有统计学意义(t=3.040、15.649,P<0.05);双侧甲状腺切除组治疗总有效率为97.67%高于对照组的65.12%,差异有统计学意义(χ^(2)=15.050,P<0.001)。结论双侧甲状腺切除术治疗甲状腺癌疗效显著,且可提升患者生活质量,改善炎症因子。
Objective To analyze the effect of bilateral thyroidectomy in thyroid cancer on inflammatory factors,quality of life,and related hormone levels.Methods A total of 86 patients with thyroid cancer admitted to the hospital from July 2019 to September 2020 were selected as the study objects.Divided into control group(unilateral gland lobe+isthmus resection surgery)and bilateral thyroidectomy group(bilateral total thyroidectomy)according to different treatment plans,43 cases in each.The levels of stress-related hormones,quality of life,curative effect,and inflammatory factors were compared between the two groups.Results There was no statistically significant difference in postoperative FT4,TT4,FT3,and TT3 between the two groups,after operation(t=0.533,0.000,0.442,0.216,P>0.05).After operation,Cor,ACTH and NE in bilateral thyroidectomy group were lower than those in control group,the difference was statistically significant(t=109.101,84.654,243.167,P<0.05).After operation,the SF-36 scores of the quality of life in the bilateral thyroidectomy group were significantly higher than those in the control group,the difference was statistically significant(P<0.05).After operation,IL-6 and CRP in bilateral thyroidectomy group were lower than those in control group,the difference was statistically significant(t=3.040,15.649,P<0.05).The total effective rate of the bilateral thyroidectomy group was 97.67%higher than that of the control group 65.12%,the diftreatment of thyroid cancer, and can improve the quality of life of patients and improve inflammatory factors.
作者
章焱华
郭元元
ZHANG Yanhua;GUO Yuanyuan(General Surgery,Nanjing Gaochun People's Hospital,Nanjing,Jiangsu Province,211300 China;Department of Anesthesiology,Nanjing Gaochun People's Hospital,Nanjing,Jiangsu Province,211300 China)
出处
《系统医学》
2022年第7期128-131,共4页
Systems Medicine
关键词
双侧甲状腺切除术
甲状腺癌
炎症因子
Bilateral thyroidectomy
Thyroid cancer
Inflammatory factors
