摘要
目的探析双相情感障碍患者非酶类抗氧化物水平及其影响因素。方法纳入在乌鲁木齐市第四人民医院住院的60例双相情感障碍患者作为研究组和参加体检的健康者60例作为正常对照组,对所有入组者均检测血浆总胆红素、白蛋白、尿酸水平。结果研究组血浆总胆红素水平高于正常对照组(P<0.05),研究组的白蛋白、尿酸水平对比正常对照组,差异无统计学意义(P>0.05)。研究组中性别和病程是血浆总胆红素水平的影响因素,男性相对女性发生血浆总胆红素水平异常的风险高(OR=5.54,P<0.05),病程>1年者相对病程<1年者发生血浆总胆红素水平异常的风险高(OR=5.80,P<0.05),汉、维吾尔族两民族因素不影响血浆总胆红素水平(OR=0.96,P>0.05)。同时,上述因素均不影响血浆白蛋白、尿酸水平(P均>0.05)。结论双相情感障碍患者非酶类抗氧化物水平受多种因素影响,积极关注风险因素,早期预防,促进疾病的康复。
Objective To explore the level of non-enzymatic antioxidants and its influencing factors in patients with bipolar disorder.Methods 60 patients with bipolar disorder hospitalized in the Fourth People's Hospital of Urumqi were included as the study group and 60 healthy people who participated in physical examination as the normal control group.The levels of plasma total bilirubin,albumin and uric acid were measured for all participants.Results The level of plasma total bilirubin in the study group was higher than that in the normal control group(P<0.05).There was no significant difference in the levels of albumin and uric acid between the study group and the normal control group(P>0.05).Gender and course of disease were the influencing factors of plasma total bilirubin level in the study group.Men had a higher risk of abnormal plasma total bilirubin level than women(OR=5.54,P<0.05).Those with a course of disease>1 year had a higher risk of abnormal plasma total bilirubin level than those with a course of disease<1 year(OR=5.80,P<0.05).The factors of Han and Uygur nationalities did not affect the plasma total bilirubin level(OR=0.96,P>0.05).At the same time,the above factors did not affect the levels of plasma albumin and uric acid(P>0.05).Conclusion The level of non-enzymatic antioxidants in patients with bipolar disorder is affected by many factors.It is wise to actively pay attention to risk factors,and with early prevention to promote the rehabilitation of the disease.
出处
《中国疗养医学》
2022年第7期766-769,共4页
Chinese Journal of Convalescent Medicine
基金
乌鲁木齐市卫生健康委科技计划项目(201901),住院双相情感障碍患者非酶类抗氧化物因子水平动态观察研究。
