摘要
目的:观察热淋清颗粒联合左氧氟沙星治疗膀胱湿热型急性肾盂肾炎的临床疗效。方法:选取急性肾盂肾炎患者106例,按随机数字表法分为对照组和观察组各53例。对照组第1~7天给予盐酸左氧氟沙星注射液治疗,第8~14天起改用乳酸左氧氟沙星片治疗;观察组在对照组的基础上给予热淋清颗粒治疗。2组疗程均为2周,比较2组临床疗效、症状消失时间以及血清C-反应蛋白(CRP)、降钙素原(PCT)水平。结果:观察组有效率为86.79%,对照组为67.92%,2组比较,差异有统计学意义(P<0.05)。观察组腰痛、发热、尿路刺激征的消失时间明显短于对照组(P<0.05)。治疗后,2组血清CRP、PCT水平均较治疗前明显降低(P<0.05),且观察组血清CRP、PCT水平明显低于对照组(P<0.05)。结论:热淋清颗粒联合左氧氟沙星治疗膀胱湿热型急性肾盂肾炎,可有效改善机体炎症反应,加速疾病康复,临床疗效显著。
Objective:To observe the clinical effect of the therapy of Relinqing granules combined with levofloxacin on acute pyelonephritis of bladder damp-heat type. Methods:A total of 106 patients with acute pyelonephritis were selected and divided into the control group and the observation group according to random number table method,with 53 cases in each group. The control group was treated with levofloxacin hydrochloride injection from Day 1 to 7,and levofloxacin lactate tablets from Day 8 to 14. The observation group was additionally treated with Relinqing granules based on the treatment of the control group. The treatment course of the two groups was two weeks. The clinical effect,symptom disappearance time and levels of serum C-reactive protein(CRP) and procalcitonin(PCT) were compared between the two groups. Results: The effective rate was 86.79% in the observation group and 67.92% in the control group, the difference being significant(P<0.05). The disappearance time of lower back pain,fever and urinary tract irritation in the observation group was significantly shorter than that in the control group(P<0.05). After treatment, the levels of serum CRP and PCT in both groups were significantly decreased when compared with those before treatment(P<0.05),and the two levels in the observation group were significantly lower than those in the control group(P<0.05). Conclusion:The therapy of Relinqing granules combined with levofloxacin has a significant clinical effect on the treatment of acute pyelonephritis of bladder damp-heat type,which can effectively improve the inflammatory responses and accelerate the recovery of the disease.
作者
王思喃
徐兴
汪丽君
WANG Sinan;XU Xing;WANG Lijun
出处
《新中医》
CAS
2022年第8期100-103,共4页
New Chinese Medicine
