摘要
目的:探究早期他汀类药物治疗对小动脉闭塞性脑梗死(SAO)的效果分析及对预后的影响.方法:选取2017年6月~2021年12月于我院治疗的80例SAO患者作为研究对象.对照组在发病1w内采用瑞舒伐他汀口服,观察组在发病24h之内采用瑞舒伐他汀口服.比较两组患者的血脂水平、神经功能、预后情况.结果:治疗后,两组患者LDL-C、TG、TC水平均低于治疗前,且观察组LDL-C、TG、TC水平低于对照组;两组患者NIHSS评分低于治疗前,且观察组低于对照组;两组患者ADL评分高于治疗前,且观察组高于对照组.结论:早期采用他汀类药物治疗,能够有效的改善SAO患者的血脂水平以及神经功能缺损的状况,还能够提高患者预后质量.
Objective To investigate the effect of early statin therapy on small artery occlusion cerebral infarction(SAO)and its influence on prognosis.Methods A total of 80 SAO patients treated in our hospital from June 2017 to December 2021 were selected as subjects.The control group was given rosuvastatin orally within lw of onset,and the observation group was given rosuvastatin orally within 24h of onset.Blood lipid level,neurological function and prognosis were compared between the two groups.Results After treatment,the levels of LDL-C,TG and TC in 2 groups were lower than before,and the levels of LDL-C,TG and TG in observation group were lower than control group.NIHSS score of 2 groups was lower than before,and observation group was lower than control group.ADL score of 2 groups was higher than before treatment,and observation group was higher than control group.Conclusion Early treatment with statins can effectively improve the level of blood lipid and neurological impairment in SAO patients,and improve the quality of prognosis.
作者
梁先发
王光曙
周著文
Liang Xian-fa;Wang Guang-shu;Zhou Zhu-wen(Department of Neurology,Tongling Maternal and Child Health Hospital,Tongling 244000,China)
出处
《湖南师范大学学报（医学版）》
2022年第2期205-207,共3页
Journal of Hunan Normal University(Medical Sciences)
关键词
他汀类药物
小动脉闭塞性脑梗死
效果分析
预后
statins
arteriolar occlusive cerebral infarction
effect analysis
the prognosis
