摘要
目的统计分析抗感染药物临床使用的不良反应情况。方法选择2017年1月至2020年11月于本院接受抗感染治疗出现不良反应的243例患者为研究病例,回顾性分析患者年龄、性别、药物种类、给药途径、不良反应发生时间、不良反应分级以及累及器官系统等资料,对抗感染药物的不良反应特点进行分析。结果使用抗感染药物后中青年群体出现不良反应的概率最高;静脉滴注相对比其他给药途径更易出现不良反应;一般在给药24h内不良反应情况较为常见;在药物种类方面,不良反应最多的分别为莫西沙星、头孢菌素类药物以及磷霉素氨丁三醇;不良反应所累及的器官系统以皮肤与其附件最为常见。结论临床使用抗感染药物时若缺乏合理性,会促进耐药菌生成,影响患者的生命健康,因此需要给予高度关注,从患者性别、年龄、药品种类、给药途径等方面制定合理方案,以提高抗感染药物使用安全性。
Objective:To statistically analyze the adverse reactions of the clinical use of anti-infective drugs.Methods:Selected 243 patients with adverse reactions from anti-infective treatment in our hospital from January 2017 to November 2020 as the study cases,and retrospectively analyzed the age,gender,drug type,route of administration,and time of adverse reactions,adverse reaction classification and organ system involvement,and analysis of the characteristics of adverse reactions of anti-infective drugs.Results:After using anti-infective drugs,the middle-aged and young male population has the highest probability of adverse reactions;intravenous drip is more prone to adverse reactions than other routes of administration;generally,adverse reactions are more common within 24 hours of administration;in terms of drug types,adverse reactions The most common reactions were moxifloxacin,cephalosporins,and fosfomycin tromethamine;the most common organ systems involved in adverse reactions were skin and its appendages.Conclusion:The lack of rationality in the clinical use of anti-infective drugs will promote the generation of drug-resistant bacteria and affect the life and health of patients.Therefore,we need to pay great attention to formulating reasonable plans in terms of patient gender,age,drug type,and route of administration.To improve the safety of anti-infective drugs.
作者
谢莹
Xie Ying(Department of Pharmacy,Juancheng County People's Hospital,Heze Shandong,274600,China)
出处
《中外女性健康研究》
2022年第8期65-66,共2页
Women＇s Health Research
关键词
抗感染药物
药品种类
给药途径
不良反应
Anti-infective drugs
Types of drugs
Route of administration
Adverse reactions
