摘要
目的观察针刺足三里、关元穴对气虚证患者临床症状及心率变异性指标的影响,并探究穴位特异性。方法将90例气虚证患者随机分为足三里组、关元组、假针刺组,每组30例。足三里组针刺双侧足三里穴,同时假针刺关元穴;关元组针刺关元穴,同时假针刺双侧足三里穴;假针刺组同时假针刺双侧足三里穴和关元穴。各组均隔日治疗,共治疗10次。治疗前后进行气虚证症状量化评分并检测患者心率变异性指标,包括时域指标的平均心率(mean HR)、全部窦性心搏R-R间期的标准差(SDNN)、24h内相邻窦性R-R间期差值的均方根(r-MSSD)和频域指标的心率变异性总功率(HRV total)、低频(LF)、高频(HF)、极低频带(VLF)、低频高频比对数值[log(LF/HF)]。结果治疗后足三里组、关元组患者气虚证症状量化评分均较本组治疗前下降,且治疗后评分均低于假针刺组,而治疗后足三里组评分又低于关元组(P<0.05)。足三里组治疗后SDNN、r-MSSD、VLF、LF、HRV total均显著增高,关元组HRV total升高,差异有统计学意义(P<0.05)。足三里组治疗后SDNN、r-MSSD、VLF、LF、HRV total显著高于关元组(P<0.05)。结论针刺足三里、关元穴可改善气虚证患者临床症状,并调控心率变异性,两者作用有差异且针刺足三里对自主神经功能调节的作用优于针刺关元穴。
Objective To observe the effect of acupuncture at Zusanli(ST36)and Guanyuan(CV4)on the symptoms and heart rate variability(HRV)in patients with qi deficiency syndrome,and to explore the acupoint specificity.Methods Totally,90 patients with qi deficiency syndrome were randomly divided into Zusanli group,Guanyuan group,and sham acupuncture group,with 30 cases in each group.In Zusanli group,bilateral Zusanli(ST36)were needled while sham acupuncture was used at bilateral Guanyuan(CV4);in Guanyuan group,bilateral Guanyuan(CV4)were needled,while sham acupuncture was used at bilateral Zusanli(ST36);in sham acupuncture group,both bilateral Zusanli(ST36)and Guanyuan(CV4)were shamly needled.All groups were treated once every other day,for 10 times in total.Before and after treatment,the score of symptoms of qi deficiency syndrome was assessed,and the HRV was detected including the mean heart rate(mean HR),the standard deviation of NN intervals(SDNN),and the root mean square of difference between adjacent NN intervals(r-MSSD)of the time domain indicators,and the total heart rate variability(HRV total),low frequency(LF),high frequency(HF),very low frequency(VLF),and log(low frequency/high frequency,LF/HF of the frequency domain indicators.ResultsThe symptom scores of qi deficiency syndrome in the Zusanli group and Guanyuan group decreased after treatment,and were lower than that of the sham acupuncture group with the lowest score in the Zusanli group(P<0.05).The SDNN,r-MSSD,VLF,LF and HRV total of the Zusanli group,as well as the HRV total of the Guanyuan group significantly increased after treatment(P<0.05).The SDNN,r-MSSD,VLF,LF,and HRV total in Zusanli group were significantly higher than those in Guanyuan group(P<0.05).Conclusion Acupuncture at Zusanli(ST36)and Guanyuan(CV4)can both improve the clinical symptoms and regulate HRV in people with qi deficiency syndrome,but the effect is different that acupuncture at Zusanli(ST36)has better effects on the regulation of autonomic nerve function than acupuncture at Guanyuan(CV4).
作者
李桐
王华
吴松
陈丽
黄琪
王雅媛
李佳
宋燕娟
王文
韩颖
毛锡顺
Gerhard Litscher
梁凤霞
LI Tong;WANG Hua;WU Song;CHEN Li;HUANG Qi;WANG Yayuan;LI Jia;SONG Yanjuan;WANG Wen;HANYing;MAOXishun;GERHARD Litscher;LIANG Fengxia(College of Acupuncture and Orthepedics,Hubei University of Chinese Medicine/Collaborative Innovation Center of Acupuncture and Moxibustion,Wuhan,430061;Department of Rehabilitation,The Central Hospital of Wuhan;Wuhan Sports University;Research Center of Traditional Chinese Medicine,Medical University of Graz,Austria)
出处
《中医杂志》
CSCD
北大核心
2022年第12期1149-1154,共6页
Journal of Traditional Chinese Medicine
基金
国家自然科学基金(81774420)
针灸治未病湖北省协同创新中心项目(HBPCIC-2016-005)。
关键词
气虚证
针刺
足三里
关元
心率变异性
自主神经系统
随机对照试验
qideficiency syndrome
acupuncture
Zusanli(ST36)
Guanyuan(CV4)
heart rate variability
autonomic nervous system
randomized controlled trial
