摘要
脂质是人体所需三大营养素之一,其全摄入链的安全和健康特性备受重视。胃肠道内含有羟基、活性氮族等多种促氧化因子,使脂质在胃肠道消化过程中易产生氧化反应。体外模拟消化相比体内消化评价具有耗时短、无伦理问题等优点,是研究脂质胃肠道消化的优选方法。同时,考虑到人体消化道环境的复杂性和脂质的多样性,消化后脂质氧化状态的真实评价也尤为关键。在研究脂质消化过程以及脂质在消化道中的氧化状态时,需要将这些方法整合利用以求对相关问题进行全面性的探索。作者介绍了脂质在体内的消化过程和目前研究脂质常用的体外消化模型,阐述了脂质消化过程中氧化产物的检测方法,对于系统研究特定脂质消化过程中的氧化机理、氧化途径具有重要意义。
Lipid is one of the three major nutrients needed by the human body,and its safety and health characteristics during the whole ingestion chain are highly valued.Pro-oxidation factors in the gastrointestinal tract,such as hydroxyl group,active nitrogen group,make lipids easy to generate oxidation reaction during gastrointestinal digestion.Compared with in vivo digestion evaluation,in vitro simulated digestion is the preferred method to study the gastrointestinal digestion of lipids since it is a timesaving method without ethical problems.At the same time,considering the complexity of human digestive tract environment and the diversity of lipids,the real evaluation of oxidation of lipids after digestion is particularly important.It is necessary to integrate and evaluate these methods to comprehensively explore the related problems when studying the process of digestion and oxidation of lipids in the digestive tract.The digestion process of lipids in vivo and the commonly used models of in vitro digestion of lipids were introduced.The detection methods of oxidation products during the digestion of lipids and the factors affecting the oxidation of lipids during digestion were described.It is very important to systematically study the oxidation mechanism and pathway of lipids during digestion.
作者
张铭凯
李晓雯
孟晨
陈亚淑
陈洪建
邓乾春
ZHANG Mingkai;LI Xiaowen;MENG Chen;CHEN Yashu;CHEN Hongjian;DENG Qianchun(School of Food Science and Engineering,Wuhan Polytechnic University,Wuhan 430048,China;Oil Crops Research Institute,Chinese Academy of Agricultural Science,Wuhan 430062,China;School of Biological Engineering and Food,Hubei University of Technology,Wuhan 430068,China)
出处
《食品与生物技术学报》
CAS
CSCD
北大核心
2022年第6期31-40,共10页
Journal of Food Science and Biotechnology
基金
国家自然科学基金项目(32001740)
湖北省自然科学基金项目(ZRMS2020002499,ZRMS2020002492)。
关键词
脂质氧化
体外消化模型
氧化产物检测
氧化影响因素
lipid oxidation
in vitro digestion model
oxidation product detection
factors affecting the oxidation
