摘要
目的:调查多重用药的肾移植受者用药情况和药学服务需求,为对其开展药学服务提供参考。方法:采用自行设计的问卷对在广州医科大学附属第二医院移植科门诊就诊或住院出院的成年肾移植受者进行调查,内容包括一般临床资料、用药情况、对肾移植术后药物治疗的认知、依从性和药学服务需求等。结果:共收集155份质量合格的问卷,其中男96例(61.93%)、女59例(38.06%),年龄(43.60±11.26)岁,初中及以下文化程度占57.42%,平均肾移植术后时间为(5.90±2.52)月;除肾脏疾病外,平均合并患有2.05种慢性病;72.90%(113例)的被调查者使用10种及以上的药物,平均用药(11.06±2.32)种;被调查者对药物治疗的认知和依从性一般,普遍缺乏对免疫抑制药物和其他常用药物的认识及合理使用知识;25.16%(39例)和39.35%(61例)的被调查者依从性被评为差和一般,服药数量在10种以上和受教育程度在初中及以下是肾移植受者依从性差的高危因素;被调查者在用药指导和健康教育方面普遍需要药学服务;在开展药学服务的形式方面,被调查者更倾向于直接交流的方式。结论:多重用药的肾移植受者对药物治疗的认知和依从性有待提高,普遍需要药学服务。为促进合理用药,临床药师极有必要参与这一特殊群体的药物治疗管理。
OBJECTIVE To investigate the drug use and pharmaceutical care needs of renal transplant recipients with polypharmacy,so as to provide reference for their pharmaceutical care.METHODS A self-designed questionnaire was distributed to adult renal transplant recipients,who were outpatients of renal transplantation department or inpatients upon discharge from the Second Affiliated Hospital of Guangzhou Medical University.The survey contents included basic clinical data,medication usage,cognition and compliance of post-transplant medication and pharmaceutical care needs.RESULTS A total of 155 effective questionnaires were collected from the adult renal transplant recipients,including 96(61.93%)males and 59(38.06%)females.Among these respondents,the mean age was(43.60±11.26)years;57.42% were with the education of junior high school or below;the mean post-transplant duration was(5.90±2.52)months.In addition to renal diseases,these patients also had 2.05 chronic diseases on average.There were 113(72.90%)respondents taking 10 or more medicines,with an average number of medicines of(11.06±2.32).The respondents lacked awareness of pharmacotherapy and showed average compliance with medication;most of them demonstrated poor knowledge of immunosuppressive drugs and other commonly used medicines.In the compliance evaluation,39(25.16%)and 61(39.35%)respondents were rated as poor and average compliance with medication.Taking more than 10 kinds of drugs and having junior high school education or below were high risk factors for poor compliance among kidney transplant recipients.The respondents generally needed pharmaceutical care in medication guidance and health education.As to the forms of pharmaceutical care,most respondents preferred direct communication.CONCLUSIONS Renal transplant recipients received polypharmacy should improve their knowledge of pharmacotherapy as well as their compliance with medication.Considering their generally needs and in order to promote rational use of drugs,it is necessary for clinical pharmacists to participate in medication therapy management for this special group.
作者
彭怀东
杨灿邦
张磊
宋文彬
陈攀
刘路浩
王若伦
PENG Huai-dong;YANG Can-bang;ZHANG Lei;SONG Wen-bin;CHEN Pan;LIU Lu-hao;WANG Ruo-lun(Department of Pharmacy,The Second Affiliated Hospital of Guangzhou Medical University,Guangdong Guangzhou 510260,China;Department of Pharmacy,Zhaoqing First People’s Hospital,Guangdong Zhaoqing 526000,China;Organ Transplant Center,The Second Affiliated Hospital of Guangzhou Medical University,Guangdong Guangzhou 510260,China;Department of Pharmacy,Kunming First People’s Hospital,Yunnan Kunming 650011,China;Department of Pharmacy,The First Affiliated Hospital of Sun Yat-sen University,Guangdong Guangzhou 510080,China)
出处
《中国医院药学杂志》
CAS
北大核心
2022年第12期1276-1281,1292,共7页
Chinese Journal of Hospital Pharmacy
基金
广州医科大学临床重点专科基金(器官移植科)(编号:010004001)
广州市卫生健康科技项目(编号:20211A010061)。
关键词
肾移植受者
多重用药
药学服务需求
renal transplant recipients
polypharmacy
pharmaceutical care needs
