摘要
目的 基于关联与聚类规则对清代古医籍所载痧疫相关病例进行探究,为临床防治急性传染性疾病提供诊疗思路。方法 检索《中华医典》中清代典籍,根据纳入及排除标准筛选与“痧”相关医案验案,应用Excel建立数据库整理归纳数据,并进行频次统计,采用SPSS软件对高频药物与主要临床表现进行关联与聚类分析。结果 高频药物有乌药、青皮、细辛等。四气方面,寒性药物的出现频率最高,温性药物的使用频率最高;五味方面,苦、甘、辛味药物的出现频率较高,而苦、辛味药物的使用频率较高;归经方面,归肺、胃、肝经药物的出现频率较高,归肝、肺、脾经药物的使用频率较高。出现频次较高的症状有发热、腹痛、神昏等。根据组间距离及药物功效将药物分为6组。结论 痧疫常伴发热、腹痛、神昏等症状,治宜消瘀透痧、辛开苦降。对清代古籍各阶段的基本处方进行分析,可为中医疫病防治提供有效诊疗思路。
Objective To explore the cases related to measles epidemic disease recorded in ancient medical books of the Qing Dynasty based on association and clustering rules, and to provide diagnosis and treatment ideas for clinical prevention and treatment of acute infectious diseases. Methods “Measles” related medical cases Chinese Medical Canon in the Qing Dynasty were retrieved, and the cases were screened according to inclusion and exclusion criteria. A database was established via Excel to perform data collation, induction, and statistical analysis for frequency. SPSS software was used to conduct correlation and cluster analysis for high-frequency drugs. Results High-frequency drugs were Linderae Radix, Citri Reticulatae Pericarpium Viride, Asari Radix Et Rhizoma, and so on. In the aspect of four qi,the occurrence frequency of cold drugs and the usage frequency of warm drugs were the highest;in the aspect of five tastes, occurrence frequency of drugs in bitter, sweet, and spicy were high, while the most usage frequency of drugs in bitter and spicy were high;in the aspect of meridian passage, the occurrence frequency of drugs in lung, stomach, and liver meridian was high;the usage frequency of drugs in liver, lung, and spleen was high. High frequency of symptoms had fever, abdominal pain, dizziness, and so on. The drugs were divided into six groups according to the distance between the groups and the efficacy of the drugs. Conclusion Measles epidemic disease is often accompanied by fever,abdominal pain, dizziness, and other symptoms, treatment should eliminate stasis and promote measles drainage, disperse with pungent medicinals and descend with bitter medicinals. The analysis of the basic prescriptions in different stages of ancient books of the Qing Dynasty can provide effective diagnosis and treatment ideas for the prevention and treatment of traditional Chinese medicine epidemic diseases.
作者
林雪宇
李剑
马源
张文风
LIN Xueyu;LI Jian;MA Yuan;ZHANG Wenfeng(School of Basic Medicine,Changchun University of Chinese Medicine,Jilin Province,Changchun130117,China)
出处
《中国医药导报》
CAS
2022年第19期142-145,共4页
China Medical Herald
基金
国家社会科学基金应急管理体系建设研究专项项目(20VYJ070)
吉林省科技发展计划项目(20190304054YY)。
关键词
湿毒疫
数据挖掘
中医疫病防治
Epidemic disease caused by dampness and toxin
Data mining
Prevention and treatment of epidemic diseases by traditional Chinese medicine
