摘要
目的探讨全飞秒激光小切口角膜基质内透镜取出术(SMILE)对屈光不正患者的疗效.方法回顾性分析146例(292眼)屈光不正患者的临床资料,按手术方式分为对照组(n=70,140眼)和观察组(n=76,152眼),对照组采用飞秒激光制瓣-激光原位角膜磨镶术(FS-LASIK)治疗,观察组采用SMILE治疗,比较两组眼表疾病指数(OSDI)、最佳矫正视力(BCVA)、裸眼视力(UCVA)、角膜荧光染色素染色评分、泪河高度(TMH)、非侵入式泪膜破裂时间(NIKBUT)、脂质层厚度、睑板腺功能评分及眼红指数(HI).结果术后1周、术后1个月和3个月,观察组OSDI评分低于对照组,NIKBUT高于对照组(P<0.05).术后1周、术后1个月和3个月,两组角膜荧光染色素染色评分、TMH、脂质层厚度、睑板腺功能评分、HI、BCVA(logMAR)、UCVA(logMAR)比较差异无统计学意义(P>0.05).结论FS-LASIK和SMILE均可改善屈光不正患者视力,但SMILE对角膜知觉损伤更小,且对眼表影响较小.
ObjectiveTo investigate the curative effect of full femtosecond laser small incision lenticule extraction(SMILE)on ametropia.MethodThe clinical data of 146 patients(292 eyes)with ametropia was retrospectively analyzed.The patients were divided into control group(n=70,140 eyes)and observation group(n=76,152 eyes)according to the surgical method.Patients in the control group were treated with femtosecond laser-assisted laser in situ keratomileusis(FS-LASIK),and those in observation group were treated with SMILE.The ocular surface disease index(OSDI),best corrected visual acuity(BCVA),uncorrected visual acuity(UCVA),corneal fluorescein staining score,tear meniscus height(TMH),non-invasive keratograph tear film breakup time(NIKBUT),lipid layer thickness,meibomian gland function score and hyperaemia index(HI)were compared between the two groups.ResultsAt 1 week,1 month and 3 months after operation,the OSDI scores of observation group were lower than those of control group,and NIKBUT was longer than that of control group,the difference was statistically significant(P<0.05).There were no significant differences in corneal fluoresce in staining,TMH,lipid layer thickness,meibomian gland function score,HI,BCVA(logMAR)and UCVA(logMAR)between the two groups at 1 week,1 month and 3 months after operation(P>0.05).ConclusionBoth FS-LASIK and SMILE can improve visual acuity of patients with ametropia,but SMILE causes less damage to corneal perception and less impact on ocular surface.
作者
覃冬
杨雯
秦岭
郭娟
孙毅
QIN Dong;YANG Wen;QIN Ling;GUO Juan;SUN Yi(Chengdu Third People’s Hospital,Chengdu 610031,China)
出处
《北华大学学报（自然科学版）》
CAS
2022年第4期504-509,共6页
Journal of Beihua University（Natural Science）
基金
四川省卫生和健康委员会科研课题(18PJ088).
关键词
屈光不正
飞秒激光
角膜基质内透镜取出术
激光原位角膜磨镶术
眼表
视力
ametropia
femtosecond laser
lenticule extraction
femtosecond laser-assisted laser in situ kerat-omileusis
ocular surface
visual acuity
