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不同膀胱内前列腺突出度预测前列腺增生患者膀胱出口梗阻的临床研究 被引量:2

The clinical study on predicting bladder outlet obstruction by different prostatic protrusion inside bladder in patients with benign prostatic hyperplasia
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摘要 目的探讨采用经腹超声测量的膀胱内前列腺突出度(IPP)与膀胱出口梗阻(BOO)相关性及其可否预测BOO。方法选择2019年11月—2021年10月在本院住院诊断为前列腺增生,并接受尿动力学检查的101例患者作为研究对象,按照不同的IPP长度分为Ⅰ组、Ⅱ组和Ⅲ组三组,Ⅰ组38例、Ⅱ组42例、Ⅲ组21例。分析三组患者前列腺症状IPSS评分、生活质量QOL评分、前列腺体积(PV)及最大尿流率(Qmax)、膀胱残余尿(PVR)、最大尿流率时逼尿肌收缩力(Pdet.Qmax)、BOO程度、膀胱出口梗阻指数(BOOI)的差异。运用相关分析计算IPP与BOOI的相关性。运用受试者工作特征曲线(ROC)计算曲线下面积(AUC),并计算IPP预测BOO的敏感度及特异度。结果三组患者的随着IPP长度的增加,IPSS评分、QOL评分、前列腺体积(PV)也随之增加,差异有统计学意义(P<0.05);三组患者的随着IPP长度的增加,膀胱残余尿(PVR)、BOO程度、膀胱出口梗阻指数(BOOI)、最大尿流率时逼尿肌收缩力(Pdet.Qmax)也随之增加,差异有统计学意义(P<0.05);三组患者的随着IPP长度的增加,最大尿流率(Qmax)随之减少,差异有统计学意义(P<0.05)。相关分析显示IPP与BOO呈正相关(γ=0.690,P<0.05)。以IPP≥11 mm作为判断膀胱出口梗阻的标准,曲线下面积为0.745,其敏感性及特异性较高。结论IPP与膀胱出口梗阻在尿动力学方面具有相关性。经腹超声测量IPP是一种有价值的评价BPH患者膀胱出口梗阻状态及程度的无创性方法。 Objective To investigate the correlation between intravesical prostatic protrusion(IPP)measured by transabdominal ultrasound and bladder outlet obstruction(BOO),to measure whether it could predict BOO.Methods The 100 patients who were diagnosed with benign prostatic hyperplasia and underwent urodynamic examination in our hospital from November 2019 to October 2021 were analyzed,and they were divided into groupⅠ(n=38),groupⅡ(n=42),and groupⅢ(n=21)according to length of IPP.The differences of score of international prostatic symptom scale(IPSS),score of quality of life(QOL)scale,prostate volume,maximum flow rate(Qmax),post-voiding residual(PVR),detrusor contractility at maximum flow rate(Pdet.Qmax),the degree of BOO,bladder outlet obstruction index(BOOI)were analyzed among different groups.The correlation analysis was used to calculate the correlation between IPP and BOOI.Receiver operating characteristic(ROC)curve was made and area under cure was calculated.The sensitivity and specificity of IPP in predicting BOO was also processed.Results With the increase of IPP length,the IPSS score,QOL score,and PV of the three groups increased,and the differences were statistically significant(P<0.05).With the increase of IPP length,the PVR,BOO degree,BOOI,and Pdet.Qmax of the three groups increased significantly,and the differences were statistically significant(P<0.05).On the contrary,the Qmax decreased with the increase of IPP,and the differences were statistically significant(P<0.05).IPP showed a positive correlation with BOO used by the correlation analysis(γ=0.690 P<0.05).Defining IPP≥11 mm as the judgment of BOO,the area under cure is 0.745,its sensitivity and specificity would be at high level.Conclusions There is a significant correlation between IPP and the degree of bladder outlet obstruction in urodynamic.Transabdominal ultrasound measurement of IPP is a useful noninvasive method that assess the presence and severity of bladder outlet obstruction in BPH patients.
作者 黄宏双 郑晓娴 晏湘山 Huang Hongshuang;Zheng Xiaoxian;Yan Xiangshan(Department of urology,the affiliated hospital of Putian University,Putian,Fujian,351100,China)
出处 《齐齐哈尔医学院学报》 2022年第9期842-845,共4页 Journal of Qiqihar Medical University
基金 莆田学院校内科研项目(2014028)。
关键词 前列腺增生 膀胱内前列腺突出度 膀胱出口梗阻 尿动力学 Benign prostatic hyperplasia Intravesical protrusion prostate Bladder outlet obstruction Urodynamics
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