摘要
目的 探讨胆肠吻合术后肝转移癌患者行射频消融术后发生感染的相关危险因素。方法 回顾性收集2010年1月至2022年4月期间,笔者所在医院行射频消融治疗的肝转移癌患者的临床资料,采用单因素及多因素logistic回归分析。结果 研究共纳入患者57例,发生术后感染19例(33.33%)。单因素logistic回归分析结果显示:肿瘤位置、肿瘤最大直径、肿瘤数目、消融次数和消融时间与RFA术后感染的发生相关(P<0.05)。进一步的多因素logistic回归分析结果显示:肿瘤位置[OR=6.45, 95%CI为(1.11,37.35),P=0.037]和消融时间[OR=1.49,95%CI为(1.16,1.91),P=0.002]是胆肠吻合术后患者行射频消融术后发生感染的独立危险因素。结论对于既往有胆肠吻合病史的转移性肝癌患者,病灶位置及消融持续时间与术后感染密切相关,应加强此类患者的术中及术后的个体化管理,促进疾病康复。
Objective To investigate the risk factors of infection after radiofrequency ablation in patients with liver metastases after choledochojejunostomy. Methods The clinical data of patients with liver metastases treated by radiofrequency ablation in our hospital from January 2010 to April 2022 were collected retrospectively and analyzed by univariate and multivariate logistic regression analysis. Results A total of 57 patients were included in the study, and the total number of postoperative infections was 19(33.33%). Univariate logistic regression analysis showed that the tumor location, maximum tumor diameter, number of tumors, ablation times, and ablation duration were related to the occurrence of infection after radiofrequency ablation(P<0.01). The results of multivariate logistic regression analysis showed that the tumor location [OR=6.45, 95%CI(1.11, 37.35), P=0.037] and ablation duration [OR=1.49, 95%CI(1.16,1.91), P=0.002] were independent risk factors for infection after radiofrequency ablation in patients with choledochojejunostomy. Conclusions For patients with metastatic liver cancer with a history of choledochojejunostomy, the tumor location and the duration of ablation are closely related to postoperative infection. We should strengthen the individualized management of such patients during and after operation should be strengthened to promote disease recovery.
作者
邹孟达
李长峰
廖轶
冯凯
毛国松
夏锋
陈志宇
张雷达
马宽生
Zou Mengda;LI Changfeng;LIAO Yi;FENG Kai;MAO Guosong;XIA Feng;CHEN Zhiyu;ZHANG Leida;MA Kuansheng(Department of Hepatobiliany Surgery,The First Afliated Hopital of Army Medical Uriversity,Chongqing 400038,P.R.Chima)
出处
《中国普外基础与临床杂志》
CAS
2022年第9期1143-1148,共6页
Chinese Journal of Bases and Clinics In General Surgery
基金
国家自然科学基金项目(项目编号:82073346)
重庆英才名家名师专项(项目编号:4246ZP112)。
关键词
胆肠吻合
转移性肝癌
射频消融
术后感染
choledochojejunostomy
metastatic hepatic carcinoma
radiofrequency ablation
postoperative infection
