摘要
目的:探讨以宫颈酸性磷酸酶(CAP)为标志物,对宫颈细胞学检查结果为未明确意义的非典型鳞状上皮细胞(ASC-US)进行辅助诊断的意义。方法:对近5年在送检本院经液基细胞学检查(TCT)被诊断为ASC-US的患者采用酸性磷酸酶免疫细胞化学染色,对结果进行统计分析。以组织学结果为金标准,判断酸性磷酸酶为标志物的诊断价值。结果:经免疫细胞化学染色后,CAP在鳞状上皮内病变患者组织细胞中阳性表达,而在炎症患者组织细胞中较少表达。结论:CAP染色能够辅助宫颈细胞学检查结果为ASC-US进行明确诊断,进一步判别是否发生病变。
Objective:To investigate the diagnostic significance of cervical acid phosphatase(CAP) as a marker for atypical squamous epithelial cells(ASC-US) whose cervical cytology results were not clear.Methods:Acid phosphatase immunocytochemical staining was performed on ASC-US patients who were diagnosed by liquid based cytology(TCT) in our hospital in recent 5 years, and the results were statistically analyzed.The diagnostic value of acid phosphatase as a marker was evaluated with histological results as the gold standard.Results:After immunocytochemical staining, acid phosphatase was positively expressed in cells of patients with squamous intraepithelial disease, but CAP was less expressed in cells of patients with inflammation.Conclusion:Acid phosphatase staining can assist in the diagnosis of ASC-US with undefined significance in cervical cytology, and further distinguish the occurrence of lesions.
作者
孔庆杨
董晓斌
王英
班宏艳
郎晓多
KONG Qingyang;DONG Xiaobin;WANG Ying(Department of Pathology,Jilin Provincial Maternal and Child Health Hospital(Jilin Provincial Obstetrics Quality Control Center),Changchun City,Jilin Province 130051;不详)
出处
《医学理论与实践》
2022年第20期3436-3438,共3页
The Journal of Medical Theory and Practice
