摘要
目的 探讨非小细胞肺癌(NSCLC)患者微创切除术后复发与转移的相关因素。方法 选择接受微创切除术的NSCLC患者88例作为研究对象,分析NSCLC患者微创切除术后复发及转移情况,并对影响术后复发及转移的相关因素进行单因素及多因素分析。结果 88例患者出院后均接受随访,在此期间内共发生复发26例,转移30例;低分化程度、Ⅱ~Ⅲ期病理分期、N1-N2期、T2-T3期、淋巴结转移数量>3个、淋巴结多站转移、已发生纵隔淋巴结转移、切除气管残端阳性对术后复发、转移均存在影响;分化程度、病理分期、N分期、T分期、淋巴结转移数量、淋巴结转移站数、纵膈淋巴结转移、切除气管残端阳性是NSCLC患者微创切除术后复发、转移的独立危险因素。结论 分化程度、病理分期、N分期、T分期、淋巴结转移数量、淋巴结转移站数、纵膈淋巴结转移、切除气管残端阳性是NSCLC患者微创切除术后复发及转移的危险因素,在治疗方案制定及选择中需充分考虑。
Objective To explore the factors related with recurrence and metastasis after minimally invasive resection in patients with non-small-cell lung cancer(NSCLC).Methods 88 NSCLC patients treated with minimally invasive resection were selected to analyze the recurrence and metastasis after minimally invasive resection in NSCLC patients and analyze single and multivariate factors affecting postoperative recurrence and metastasis.Results All 88 patients were followed up after discharge,26 recurrence had 30 metastasis,low degree of differentiation,stage pathological stage,stage N1-N2,stage T2-T3,> 3,lymph node metastasis,positive mediastinal lymph node metastasis,postoperative recurrence and metastasis,and differentiation,pathological stage,N stage,T stage,lymph node metastasis number,lymph node metastasis,mediastinal lymph node metastasis and resection were independent risk factors for minimally invasive recurrence and metastasis in NSCLC patients.Conclusion The degree of differentiation,pathological stage,N stage,T stage,lymph node metastasis number,lymph node metastasis stations,mediastinal lymph node metastasis,and positive tracheal residue resection are the risk factors for recurrence and metastasis after minimally invasive resection of NSCLC patients,and they should be fully considered in the formulation and selection of treatment plan.
作者
王楠
姜京京
梁珊珊
陈培
乔朋丽
刘芳芳
李莉
WANG Nan;JIANG Jingjing;LIANG Shanshan(The First Affiliated Hospital of Zhengzhou University,Zhengzhou,450000)
出处
《实用癌症杂志》
2022年第10期1635-1638,共4页
The Practical Journal of Cancer
关键词
非小细胞肺癌
微创切除术
术后复发
转移
因素分析
Non-small cell lung cancer
Minimally invasive resection
Postoperative recurrence
Metastasis
Factor analysis
