摘要
目的探讨营养支持在老年肺结核合并营养不良患者中的作用效果。方法回顾性研究2019年5月至2021年5月在宁夏回族自治区第四人民医院住院的存在营养风险的126例老年肺结核确诊患者,其中60例采用营养支持治疗的患者作为实验组,66例未予以营养支持治疗的患者作为对照组,采用常规抗结核及一般治疗。比较两组患者治疗1个月后一般临床特征、实验室指标、影像学特点等差异。结果两组患者临床表现主要为咳嗽、咳痰、乏力,占比分别为76.2%、64.3%、55.6%。两组患者影像学表现主要以斑片影、结节、树芽征、空洞、磨玻璃影、实变、支气管壁增厚、肿块、条索灶为主;对照组痰菌转阴时间、住院总天数和乳酸含量均高于实验组(P均<0.05),白蛋白数、血红蛋白数、淋巴细胞计数均低于实验组(P均<0.05);实验组有52例(86.7%)患者病灶吸收,8例(13.3%)患者病灶进展,对照组有49例(74.2%)患者病灶吸收,17例(25.8%)患者病灶进展,两组患者影像学病灶吸收情况差异无统计学意义(P>0.05)。结论营养支持在老年肺结核合并营养不良患者治疗过程中有一定的使用价值,可以缩短痰菌阴转时间及住院时间,改善患者营养状态及免疫功能。
Objective To investigate the effect of nutritional support in elderly patients with tuberculosis combined with malnutrition.Methods A retrospective study of 126 elderly patients with confirmed pulmonary tuberculosis at nutritional risk who were hospitalized at Fourth People's Hospital of Ningxia Hui Autonomous Region from May 2019 to May 2021,60 of whom were treated with nutritional support as the experimental group and 66 patients who were not treated with nutritional support as the control group,with conventional anti-tuberculosis and general treatment.The differences in general clinical characteristics,laboratory indices,and imaging features were compared between the two groups of patients after 1 month of treatment.Results The clinical manifestations of patients in the two groups were mainly cough,sputum and weakness,accounting for 76.2%,64.3%and 55.6%respectively.The imaging manifestations of patients in both groups were mainly patchy shadow,nodule,tree bud sign,cavity,ground glass shadow,solid change,bronchial wall thickening,mass,and striated foci;the sputum bacteria conversion time,total hospital days and lactate content were higher in the control group than in the experimental group(P all<0.05),and the albumin count,hemoglobin count and lymphocyte count were lower than in the experimental group(P all<0.05);52 patients in the experimental group(86.7%)of patients in the experimental group had lesion absorption and 8 cases(13.3%)had lesion progression,while 49 cases(74.2%)of patients in the control group had lesion patient lesion absorption and 17 cases(25.8%)had lesion progression,and the difference in imaging lesion absorption between the two groups was not statistically significant(P>0.05).Conclusion Nutritional support is valuable in the treatment of elderly patients with pulmonary tuberculosis combined with malnutrition,which can shorten the time to negative sputum and hospitalization,and improve the nutritional status and immune function of patients.
作者
刘伯飞
户淑红
杨继黎
刘广天
王芳
赵丽
李昕
陈冲
LIU Bofei;HU Shuhong;YANG Jili;LIU Guangtian;WANG Fang;ZHAO Li;LI Xin;CHEN Chong(Department of Critical Care Medicine,Fourth People's Hospital of Ningxia Hui Autonomous Region,Yinchuan 750021,China;Xingguangxiang Community Health Station,Fourth People's Hospital of Ningxia Hui Autonomous Region,Yinchuan 750021,China;Prevention and Treatment Department,Fourth People's Hospital of Ningxia Hui Autonomous Region,Yinchuan 750021,China;Pulmonary Function Unit,Department of Respiratory and Critical Care Medicine,General Hospital of Ningxia Medical University,Yinchuan 750004,China;Department of Medical Science,Fourth People's Hospital of Ningxia Hui Autonomous Region,Yinchuan 750021,China)
出处
《宁夏医科大学学报》
2022年第9期903-907,共5页
Journal of Ningxia Medical University
关键词
肺结核
老年
营养不良
营养支持
免疫功能
tuberculosis
the elderly
malnutrition
nutrition support
immune function
