摘要
目的:评估经牙槽嵴顶入路的上颌窦底黏膜提升术和经侧壁开窗的上颌窦底黏膜提升术治疗上颌后牙区骨量不足中黏膜穿孔率,为临床制定治疗方案提供医学证据。方法:通过检索PubMed、EMBASE、Cochrane library、CNKI、万方、维普等数据库,全面收集有关两种术式穿孔率比较的相关文献。检索语言为中文和英文,对纳入的文献按照Cochrane系统评价方法并提取相关论文的特征信息,采用穿孔例数作为指标评价两种术式的安全性,应用Review manager 5.3软件,根据文献异质性检验结果采用相应的模型进行Meta分析,接着对统计结果逐一进行敏感性分析,最后通过漏斗图分析评估是否存在发表偏倚。结果:通过检索各个数据库得到558篇文献,经过多次筛选共14篇文献纳入本次研究,经Meta分析结果显示:合并效应量RR=1.98,95%CI(1.21,3.22),总体检验效应差异有统计学意义(Z=2.73,P=0.006)。敏感性分析结果表明逐一剔除每篇文献后对最终结果影响不大。Egger’s定量偏倚风险检验表明发表性偏倚不明显对合并的效应量基本可以忽略(P=0.301)。结论:本研究两种入路方式在上颌窦底骨增量手术过程中穿孔率有明显统计学差异,上颌窦内提升术穿孔率高于上颌外提升术穿孔率。
Objective:To evaluate the perforation rate of mucous membrane in the treatment of bone deficiency in maxillary posterior dental region by mucous membrane lifting through alveolar crest approach and mucous membrane lifting through lateral wall window,and to provide medical evidence for clinical treatment.Method:Through retrieval of PubMed,EMBASE,Cochrane Library,CNKI,Wanfang,Weipu and other databases,comprehensive literature on the comparison of perforation rates between two surgical procedures was collected.The retrieval languages were Chinese and English.For the included literatures,Cochrane systematic evaluation method was used to extract the characteristic information of relevant papers.The number of perforation cases was used as an indicator to evaluate the safety of two surgical procedures.Using Review Manager 5.3 software,Meta analysis was conducted based on the results of literature heterogeneity test using corresponding models,followed by sensitivity analysis of statistical results one by one,and finally the existence of publication bias was evaluated by funnel plot analysis.Result:Five hundred and fifty-eight literatures were retrieved from various databases,and a total of 14 literatures were included in this study after multiple screening.Meta-analysis results showed that the combined effect size RR=1.98,95%CI (1.21,3.22),the overall test effect was statistically significant (Z=2.73,P=0.006),the results of sensitivity analysis showed that the elimination of each article had little effect on the final results.Egger’s quantitative bias risk test showed that the effect size of the merger could be ignored if the publication bias was not obvious (P=0.301).Conclusion:There is significant statistical difference in the perforation rate between two approaches in the process of maxillary sinus floor incremental bone surgery,and the perforation rate of maxillary sinus lift is higher than that of external maxillary lift.
作者
陈佳怡
陆一平
华臻
徐进
黄小勇
朱伟强
CHEN Jiayi;LU Yiping;HUA Zhen;XU Jin;HUANG Xiaoyong;ZHU Weiqiang(Suzhou City Wujiang District Second People’s Hospital,Suzhou 215000,China)
出处
《中外医学研究》
2022年第29期168-172,共5页
CHINESE AND FOREIGN MEDICAL RESEARCH
