摘要
金圣草黄素是一种天然黄酮化合物,存在于多种中药和药用植物体内,具有良好的新药候选化合物潜力。近年来,随着金圣草黄素及其糖苷类衍生物的药效作用和药理机制研究逐渐增多,该化合物的药理作用特点逐渐显现,尤其是在抗肿瘤、抗氧化损伤和抗炎免疫调节等多个领域显示出良好的新药候选化合物开发潜力。本文通过对金圣草黄素的药理作用和机制进行简要综述,为研究者了解该化合物的药理作用特点,同时也为基于该成分的新药开发提供借鉴和参考。
Chrysoeriol is a natural flavonoid compound,which is widely present in many kinds of traditional Chinese medicine and medicinal herbs.In recent years,studies of Chrysoeriol on the pharmacological effects and its glycosides have gradually increased,especially in anti-tumor,anti-oxidative damage and anti-inflammatory immune regulation,etc.,showing good pharmacological effects,and it has prospective potency as a candidate to develop new drug in those domain.This article briefly reviews the pharmacological effects and underlying mechanisms of chrysoeriol,so that researchers can understand the pharmacological characteristics of this compound,and also provide references for the development of new drugs based on this ingredient.
作者
邓颖
白殊同
DENG Ying;BAI Shutong(Department of Gynecology,Chongqing Hospital of Traditional Chinese Medicine,Chongqing 400021,China;Chongqing Key Laboratory of Traditional Chinese Medicine to Prevent and Treat Autoimmune Diseases,Chongqing Hospital of Traditional Chinese Medicine,Chongqing 400021,China)
出处
《中国临床药理学与治疗学》
CAS
CSCD
2022年第10期1155-1162,共8页
Chinese Journal of Clinical Pharmacology and Therapeutics
基金
重庆市卫生健康委员会中医药科研项目青年项目(2021ZY4108)
重庆市科学技术局科研院所绩效激励引导专项(cstc2018jxjl130034)。
关键词
金圣草黄素
抗肿瘤
抗炎免疫调节
抗氧化
研究进展
chrysoeriol
antitumous effect
anti-inflammatory and immunoregulation
antioxidant
research advance
