摘要
目的分析米索前列醇和缩宫素治疗产后出血的临床作用;方法经我院医学伦理委员会审批,并征得患者同意的基础上,使用医学统计学分析方法,设置样本对象对于我院分娩的,确诊为妊娠高血压综合征患者;设置选取时段为2019年6月至2020年8月。设置选取例数为66,设置分组方法为:随机数字。形成分组结果为对照组33例与观察组33例,对照组使用缩宫素进行干预,观察组联合使用缩宫素与米索前列醇。统计患者产后2小时出血量、产后24小时出血量及第三产程时间,统计患者宫缩恢复时间与血红蛋白情况,统计患者不良反应发生情况;结果观察组产后2小时出血量低于200ml,产后24小时出血量低于35ml。第三产程时间为7.12±4.23分钟,均显著低于对照组,差异均具有统计学意义(P=0.001);观察组宫缩恢复时间为30.27±5.23分钟,显著低于对照组。治疗开始前,患者血红蛋白统计数值均超过140g/L,统计数值较高,差异无统计学意义(P>0.05)。经过治疗后,患者血红蛋白统计数值均实现了一定程度的下降,观察组统计数值为102.41±9.12g/L,显著低于对照组,差异具有统计学意义(P=0.001);观察组不良反应发生率低于5%,对照组超过9%,相比结果提示观察组较低,差异不具有统计学意义(P>0.05)。结论米索前列醇和缩宫素治疗产后出血能实现较好的临床效果,患者产后2小时与产后24小时出血量显著低于对照组,且不良反应较低。建议在临床治疗中推广、使用。
Objective To analyze the clinical effects of misoprostol and oxytocin in the treatment of postpartum hemorrhage.Methods On the basis of the approval of the medical ethics Committee of our hospital and the consent of the patients,medical statistical analysis method was used to set the sample objects for the patients who delivered in our hospital and were diagnosed as gestational hypertension syndrome.Set the selection period from June 2019 to August 2020.Set the number of selected cases to 66,and set the grouping method to random number.The results were divided into the control group(33 cases)and the observation group(33 cases).The control group received oxytocin intervention,and the observation group received oxytocin combined with misoprostol.The patient's blood loss at 2 hours postpartum,24 hours postpartum and the time of the third stage of labor were counted,the recovery time of the patient's contractions and hemoglobin were counted,and the occurrence of adverse reactions were counted.Results the blood loss of the observation group was less than 200ml at 2 hours postpartum and 35ml at 24 hours postpartum.The time of the third stage of labor was 7.12±4.23 minutes,which was significantly lower than that of the control group,with statistical significance(P=0.001).The recovery time of uterine contractions in the observation group was 30.27±5.23 minutes,significantly lower than that in the control group.Before the treatment,the statistical values of hemoglobin in all patients were higher than 140g/L,and the difference was not statistically significant(P>0.05).After treatment,the statistical value of hemoglobin in all patients decreased to a certain extent.The statistical value of the observation group was 102.41±9.12g/L,which was significantly lower than that of the control group(P=0.001).The incidence of adverse reactions was less than 5%in the observation group and more than 9%in the control group,which was lower than the observation group and the difference was not statistically significant(P>0.05).Conclusion Misoprostol and oxytocin can achieve good clinical effect in the treatment of postpartum hemorrhage.The bleeding amount of patients at 2 hours postpartum and 24 hours postpartum is significantly lower than the control group,and the adverse reactions are lower.It is recommended to be popularized and used in clinical treatment.
作者
张秀颖
Zhang Xiuying(Daqing Longnan Hospital/The Fifth Affiliated Hospital of Qiqihar Medical College,Heilongjiang Daqing 163453)
出处
《实用妇科内分泌电子杂志》
2021年第13期27-29,共3页
Electronic Journal of Practical Gynecological Endocrinology
关键词
产后出血
米索前列醇
缩宫素
postpartum hemorrhage
Misoprostol
oxytocin
