摘要
目的:研究经皮肾镜取石术(PCNL)、输尿管镜气压弹道碎石术(URSL)及体外冲击波碎石术(ESWL)治疗肾结石患者的临床观察及对其血清尿激酶及甲状腺素水平的影响.方法:以2018年1月至2020年8月在本院进行治疗的300例肾结石患者作为研究对象.将患者随机分为PCNL组、URSL组和ESWL组,每组100例.比较三组患者的治疗效果、围手术期指标、血清尿激酶与甲状腺素水平以及不良反应发生率.结果:PCNL组患者的结石完全清除率显著高于URSL组及ESWL组(P<0.05);URSL组与PCNL组的术中出血量及术后住院时间分别比较,差异均无统计学意义(P>0.05);术后3个月,三组患者的血清尿激酶水平显著升高,甲状腺素水平显著下降(P<0.05);三组患者肾绞痛、发热、血尿以及恶心呕吐等不良反应发生率比较,差异无统计学意义(P>0.05).结论:相比URSL、ESWL,PCNL治疗肾结石,适应性更广,治疗效果更显著.
Objective:To study the clinical observation of percutaneous nephrolithotomy(PCNL),pneumatic lithotripsy(URSL)and extracorporeal shock wave lithotripsy(ESWL)in the treatment of renal calculi and its influence on the levels of serum urokinase and thyroxine.Methods:Three hundred patients with renal calculi treated in our hospital from January 2018 to August 2020 were selected.The patients were randomly divided into PCNL group,URSL group and ESWL group.The treatment effect,perioperative indicators,levels of serum urokinase and thyroxine and complications of the three groups were compared.Result:Patients in the PCNL group had a significantly higher rate of complete stone clearance than patients in the URSL group and the ESWL group(P<0.05).The differences in intraoperative blood loss and postoperative hospital stay between the URSL and the PCNL groups were not statistically significant(P>0.05).After treatment,the levels of serum urokinase significantly increased and the levels of thyroxine significantly decreased in the three groups(P<0.05).There were no significant differences among the three groups in the occurrence of complications(P>0.05).Conclusion:Compared with URSL and ESWL,PCNL has wider indications and more significant therapeutic effect in the treatment of kidney stones.
作者
吕文伟
魏澎涛
张寒
刘红燕
黄明辉
LYU Wen-wei;WEI Peng-tao;ZHANG Han;LIU Hong-yan;HUANG Ming-hui(Department of Urology,Luoyang Central Hospital Afiliated to Zhengzhou University,Luoyang 471000;Health care department of Luoyang Central Hospital Affiliated to Zhengzhou University,Luoyang 471000,China)
出处
《四川解剖学杂志》
2022年第2期32-34,共3页
Sichuan Journal of Anatomy
关键词
经皮肾镜取石术
输尿管镜气压弹道碎石术
体外冲击波碎石
结石清除率
Percutaneous nephrolithotomy
Ureteroscopic pneumatic lithotripsy
Extracorporeal shock wave lithotripsy
Stone clearance rate
