摘要
目的通过CT影像重构三维血管模型,研究外加均匀磁场对血液动力学行为的影响规律。方法采用计算流体动力学理论和磁流体力学方法,建立体外均匀磁场对血液流动影响的数学模型,运用多物理场耦合模拟软件COMSOL Multiphysics进行仿真模拟,探究磁场强度对血液流动速度、压力和剪切应力的影响。结果随着磁场强度的增加,血管中心处的流速受到了更加显著的抑制。壁面压力随着磁场强度的增加而减小,且磁场在血流分叉前对壁面处压力的影响明显,而在血流分叉后对壁面压力的影响减弱。血流进入分支血管后,壁面切应力显著增加,同时磁场对切应力的影响也显著增强。结论人体血液具有磁流体力学特性,一定强度范围的磁场对血液流动产生了明显的影响。研究结果为设计人造强磁场设备、评估人造磁场环境对人体血液动力学的影响以及诊断人造磁场环境产生的疾病提供理论依据。
Objective To reconstruct three⁃dimensional vascular model bases on CT images,and to study the influence patters of external uniform magnetic field on hemodynamic behavior.Methods The mathematical model of blood flow with external uniform magnetic field was established by using the theory of computational fluid dynamics and the method of magnetohydrodynamics.The simulation was carried out by using the multi⁃physical field coupling simulation software COMSOL Multiphysics to explore the effects of magnetic field intensity on blood flow velocity,pressure and shear stress.Results The magnetic field significantly suppressed the velocity at the center of blood vessel with magnetic field intensity increasing.The wall pressure decreased with magnetic field intensity increasing,and the influence of magnetic field on wall pressure before blood flow bifurcation was obvious,but the influence on wall pressure after blood flow bifurcation was weak.After blood flow entered the branch vessel,the wall shear stress increased significantly,and the effect of magnetic field on shear stress also increased significantly.Conclusions Human blood has magnetohydrodynamic characteristics,and the magnetic field in a certain intensity range has a significant impact on blood flow.The results provide a theoretical basis for the design of artificial equipment with high intensity magnetic field,evaluation for the effects of artificial magnetic field on human hemodynamics,and diagnosis of the diseases caused by artificial magnetic field.
作者
刘雪洁
田帅
崔红社
常家鹏
张敬奎
LIU Xuejie;TIAN Shuai;CUI Hongshe;CHANG Jiapeng;ZHANG Jingkui(School of Environmental and Municipal Engineering,Qingdao University of Technology,Qingdao 266033,Shandong,China;The Eighth Affiliated Hospital of Sun Yat-Sen University,Shenzhen 518033,Guangdong,China;College of Energy and Mechanical Engineering,Shanghai University of Electric Power,Shanghai 200090,China)
出处
《医用生物力学》
CAS
CSCD
北大核心
2022年第5期933-939,共7页
Journal of Medical Biomechanics
基金
山东省自然科学基金项目(ZR2019QEE040)。
关键词
血液动力学
分叉颈动脉血管
磁场
磁流体力学
速度场
剪切应力
hemodynamics
bifurcated carotid artery vessels
magnetic field
magnetohydrodynamics
velocity field
shear stress
