摘要
目的分析基于食物黏稠度调整的营养摄入方法对喉癌术后放疗患者免疫和营养功能的影响。方法选取南京大学医学院附属鼓楼医院肿瘤科2017年11月至2021年10月收治的296例喉癌手术后放疗患者,采取随机数字表法将其分为研究组(148例)和对照组(148例)。研究组实施基于食物黏稠度调整的营养摄入方法,对照组实施常规饮食健康指导,比较两组2个月后的营养状态和免疫功能指标。结果干预后,两组白蛋白、前白蛋白、转铁蛋白均高于干预前,且研究组高于对照组,差异有统计学意义(P<0.05)。两组CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)水平均高于干预前,且研究组高于对照组,差异有统计学意义(P<0.05)。结论喉癌术后放疗患者接受基于食物黏稠度调整的营养摄入饮食健康指导,可有效恢复和稳定营养状态,增强免疫功能,有助于促进疾病转归,具有临床研究和推广价值。
Objective To analyze the influence of nutrient intake method based on food viscosity adjustment on the immunity and nutritional function in patients with radiotherapy after laryngeal cancer surgery.Methods A total of 296 patients with radiotherapy after laryngeal cancer surgery admitted to the Department of Oncology,Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School from November 2017 to October 2021 were selected and divided into study group(148 cases)and control group(148 cases)by random number table method.The study group received nutrition intake method based on food viscosity adjustment,while the control group received routine dietary health guidance.The nutritional status and immune function indexes of the two groups were compared after two months.Results After intervention,albumin,prealbumin,and transferrin in two groups were higher than those before intervention,and the study group was higher than the control group,the differences were statistically significant(P<0.05).The levels of CD3^(+),CD4^(+),CD4^(+)/CD8^(+)in both groups were higher than those before intervention,and the study group was higher than the control group,the differences were statistically significant(P<0.05).Conclusion The implementation of nutrition intake dietary health guidance based on food viscosity adjustment for patients with radiotherapy after laryngeal cancer surgery can effectively restore and stabilize the nutritional state,enhance immune function,and contribute to promoting the outcome of the disease,which has clinical research and promotion value.
作者
庄羽
汪娟
卞丽娟
ZHUANG Yu;WANG Juan;BIAN Lijuan(Department of Oncology,Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School,Jiangsu Province,Nanjing210000,China;Tumor Center,Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School,Jiangsu Province,Nanjing210000,China)
出处
《中国医药导报》
CAS
2022年第35期169-171,180,共4页
China Medical Herald
基金
江苏省卫生计生委科研课题项目(H2018111)。
关键词
食物黏稠度
喉癌
手术治疗
放疗
免疫功能
营养状态
Food viscosity adjustment
Laryngeal cancer
Surgical treatment
Radiotherapy
Immune function
Nutritional status
