摘要
目的 在治疗湿热蒸盛型手足口病中,给予患儿采取清瘟败毒饮联合中药熏洗进行治疗,分析清瘟败毒饮联合中药熏洗的安全性与有效性。方法 以2020年1月至2022年1月作为本次研究时间,选择我院接收的70例湿热蒸盛型手足口病患儿,采用盲目法分为对照组35例(中药熏洗)与观察组35例(清瘟败毒饮联合中药熏洗),比较两组治疗总疗效、免疫功能水平变化、炎性因子变化、症状消失时间以及安全性。结果 与对照组相比较,观察组的临床治疗总疗效更高,观察组的口腔溃疡恢复时间、体温恢复正常时间、手足皮疹消失时间以及住院时间更短。治疗后观察组的Ig A水平(1.45±0.03)g/L高于对照组Ig A水平(1.32±0.05)g/L,观察组的Ig M水平(1.42±0.08)g/L高于对照组Ig M水平(1.23±0.05)g/L,观察组的Ig G水平(9.39±1.46)g/L高于对照组(9.01±1.48)g/L。治疗后观察组的CRP水平(10.65±2.51)mg/L低于对照组(12.32±3.44)mg/L,治疗后观察组的IL-6水平(20.12±4.24)ng/L低于对照组(25.23±3.56)ng/L,观察组的TNF-α水平(31.21±4.46)ng/L低于对照组(37.38±4.48)ng/L,组间相关数据有统计学差异(P<0.05)。观察组的不良反应发生率11.43%,对照组的不良反应发生率8.57%(P>0.05)。结论 在治疗湿热蒸盛型手足口病中,通过采用清瘟败毒饮联合中药熏洗进行治疗取得了比较确切的临床效果,对患者的临床多数症状具有良好的改善效果,增强患儿的免疫功能,降低患者的者炎性反应,促进患儿早日恢复,并且清瘟败毒饮联合中药熏洗用药比较安全,值得推荐。
Objective In the treatment of hand-foot-mouth disease due to excessive dampness and heat, children were treated with Qingwen Baidu decoction combined with fumigation and washing with Chinese medicine, and the safety and effectiveness of Qingwen Baidu decoction combined with fumigation and washing with Chinese medicine were analyzed. Methods From January 2020 to January 2022, 70 children with hand, foot and mouth disease due to excessive damp-heat were selected and randomly divided into the control group(35 cases, traditional Chinese medicine fumigation) and the observation group(35 cases, Qingwen Baidu decoction combined with traditional Chinese medicine fumigation). The total therapeutic effect, immune function level, inflammatory factors, symptom disappearance time and safety of the two groups were compared.Results Compared with the control group, the total clinical curative effect of the observation group was higher, and the recovery time of oral ulcer,the recovery time of body temperature, the disappearance time of hand and foot rash and the hospitalization time of the observation group were shorter. After treatment, the IgA level of the observation group(1.45±0.03) g/L was higher than that of the control group(1.32±0.05) g/L;The IgM level of the observation group(1.42±0.08) g/L was higher than that of the control group(1.23±0.05) g/L;The IgG level in the observation group(9.39±1.46) g/L was higher than that in the control group(9.01±1.48) g/L. The CRP level in the observation group(10.65±2.51) mg/L was lower than that in the control group(12.32±3.44) mg/L after treatment;The IL-6 level in the observation group(20.12±4.24) ng/L was lower than that in the control group(25.23±3.56) ng/L after treatment;The TNF-α level in the observation group(31.21±4.46) ng/L was lower than that in the control group(37.38±4.48) ng/L. The relevant data were statistically different between groups(P<0.05). The incidence of adverse reactions in the observation group was 11.43%, and that in the control group was 8.57%(P>0.05). Conclusion In the treatment of hand, foot and mouth disease due to excessive dampness and heat, Qingwen Baidu decoction combined with fumigation and washing with traditional Chinese medicine has achieved definite clinical effect, which has a good improvement effect on most clinical symptoms of patients, enhances the immune function of children, reduces the inflammatory reaction of patients, and promotes the early recovery of children. Qingwen Baidu decoction combined with fumigation and washing with traditional Chinese medicine is safe and worthy of recommendation.
作者
刘伟
WEI Liu(Luxi County Maternal and Child Health Hospital,Luxi 337200,China)
出处
《中国医药指南》
2023年第3期132-135,共4页
Guide of China Medicine
关键词
清瘟败毒饮
中药熏洗
小儿手足口病
湿热蒸盛型
临床效果
安全性
Qingwen Baidu decoction
Fumigation and washing of traditional Chinese medicine
Hand
foot and mouth disease in children
Dampheat type
Clinical effect
Security
