摘要
慢性阻塞性肺疾病急性加重是造成老年人死亡的重要原因之一,早期诊断、治疗干预与预后判断是阻止病情发展的关键。大量研究表明,生物标志物在该病的病因诊断、病情评估、预后及治疗方面发挥重要的辅助作用。本文总结了一系列与慢性阻塞性肺疾病相关的生物标志物在慢性阻塞性肺疾病急性加重的风险预测、诊断以及预后评估方面的应用。
Acute exacerbation of chronic obstructive pulmonary disease(COPD)is one of the leading causes of death in the elderly.Early diagnosis,treatment intervention,and prognosis identification are the keys to preventing the development of the disease.A large number of studies have shown that biomarkers play an important auxiliary role in the etiological diagnosis,assessment,prognosis,and treatment of the disease.This article summarizes the application of a series of COPD-related biomarkers in risk prediction,diagnosis,and prognosis assessment of acute exacerbation of COPD.
作者
申普
李乔玉
张静
陈亚红
Shen Pu;Li Qiaoyu;Zhang Jing;Chen Yahong(Department of Respiratory and Critical Care Medicine,the Third Hospital of Peking University,Chronic Airway Disease Research Center of Peking University Medical Department,Beijing 100191,China)
出处
《国际呼吸杂志》
2022年第24期1874-1881,共8页
International Journal of Respiration
基金
2020年度首都卫生发展科研专项项目(首发2020-2Z-40917)
北京大学第三临床医院建设队列建设项目(BYSYDL2021013)。
关键词
肺疾病
慢性阻塞性
急性加重
生物标志物
Pulmonary disease,chronic obstructive
Acute exacerbation
Biomarkers
