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等渗对比剂在冠状动脉CTA检查中的应用研究 被引量:1

Application of isotonic contrast agent in examination of coronary artery CTA
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摘要 目的探讨等渗与次高渗对比剂在冠状动脉CT血管造影(CTA)检查中的应用。方法回顾性分析2020年1-12月在重庆市急救医疗中心行冠状动脉CTA检查的240例患者病例资料。等渗组采用碘克沙醇320 mgI/mL,次高渗组采用碘海醇350 mgI/mL,比较两组对比剂推注后受检者心率及不良反应发生情况;对图像质量进行主观评价和客观评价(测量冠状动脉不同分支,计算对比噪声比)。结果等渗组心率(72.12±4.64)次/分钟低于次高渗组(77.35±5.78)次/分钟,比较差异有统计学意义(P<0.05)。两组受检者注入对比剂10 s内发热程度及尿意感程度比较差异均有统计学意义(P<0.05)。等渗组图像质量明显好于次高渗组(P<0.05)。结论冠状动脉CTA检查使用等渗对比剂碘克沙醇320 mgI/mL,可使受检者心率相对稳定,减少采集图像时的心率波动,提高图像质量。 Objective To investigate the clinical application of isotonic and sub-hypertonic contrast agent in coronary computed tomography angiography(CTA).Methods The medical data of 240 patients with coronary CTA examination in the Chongqing Municipal Emergency Medical Center from January to December 2020 were retrospectively analyzed.The isotonic group adopted Iodixanol 320 mgI/mL and the sub-hypertonic group adopted Iohexol 350 mgI/mL.The heart rate and adverse reactions occurrence after injection of contrast were compared between the two groups.The subjective assessment and objective assessment on the image quality were performed(measuring the different coronary branches and calculating the contrast to noise ratio).Results The heart rate in the isotonic group was(72.12±4.64) beats/min, which was lower than(77.35±5.78) beats/min in the sub-hypertonic group, and the difference was statistically significant(P<0.05).There were statistically significant differences in the degree of fever and urination desire within 10 s after contrast injection between the two groups(P<0.05).The image quality in the isotonic group was significantly better than that in the sub-hypertonic group(P<0.05).Conclusion Using isotonic contrast Iodixanol 320 mgI/mL in the coronary CTA examination could keep the patient’s heart rate relatively stable, reduce the heart rate fluctuation during the acquisition of images, and improve the image quality.
作者 李随丽 彭超 刘羽 黄英 丁祥利 LI Suili;PENG Chao;LIU Yu;HUANG Ying;DING Xiangli(Department of Medical Image,Chongqing Municipal Emergency Medical Center/Chongqing Municipal Fourth People’s Hospital,Chongqing 400014,China;Department of Radiology,Chongqing Municipal Public Health Medical Emergency Center,Chongqing 400000,China)
出处 《重庆医学》 CAS 2023年第2期221-224,共4页 Chongqing medicine
基金 国家科技部“重点研发计划项目”子项目(2018YFC0114404)。
关键词 冠状动脉CT血管造影术 等渗对比剂 次高渗对比剂 心率 图像质量 coronary computed tomographic angiography isotonic contrast agent sub-hypertonic contrast agent heart rate image quality
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