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穴位贴敷疗法治疗类风湿性关节炎疗效的Meta分析

Meta Analysis of the effect of acupoint sticking application for rheumatoid arthritis
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摘要 目的系统评价穴位贴敷疗法治疗类风湿性关节炎的疗效,为临床提供循证依据。方法检索中国知网、万方、维普、中国生物医学文献数据库和PubMed、Embase、Cochrane图书馆,经2人独立筛选确定纳入研究文献,通过Cochrane手册“偏倚风险评估”工具对文献质量评价,采用Review Manager 5.3软件进行meta分析。结果穴位贴敷疗法联合常规西药治疗类风湿性关节炎比常规西药总有效率高[OR=3.32,95%CI(1.87,5.90),Z=4.10,P<0.01];视觉模拟评分(VAS)方面,穴位贴敷疗法优于其他组别[SMD=-0.42,95%CI(-0.66,-0.18),Z=3.46,P<0.01];穴位贴敷疗法联合常规西药缓解类风湿性关节炎临床症状上优于常规西药[晨僵时间:MD=-11.95,95%CI(-17.73,-6.17),Z=4.05,P<0.01;关节肿胀:MD=-1.75,95%CI(-2.07,-1.43),Z=10.72,P<0.01;关节压痛:MD=-1.88,95%CI(-2.33,-1.43),Z=8.14,P<0.01]。结论穴位贴敷疗法可以提高类风湿性关节炎临床疗效,未来尚且需要多中心、大样本、高质量的临床研究进行佐证。 Objective To systematically evaluate the effect of acupoint sticking application for rheumatoid arthritis,and to provide clinical evidence-based.Methods Literatures were avail⁃able by searching the database including CNKI,Wanfang Data,VIP,CBM,PubMed,Embase and Cochrane library,and then two independent researchers respectively screened and determined the final inclusion literatures in the study.Using Assessing risk of bias in Cochrane Handbook evaluated the quality of literatures,and finally made a Meta analysis using Rev Man 5.3 software.Results Acupoint sticking application combined with conventional western medicine was more efficient than conventional western medicine(OR=3.32,95%CI[1.87,5.90],Z=4.10,P<0.01);Acupoint sticking application was superior to other groups in VAS respect(SMD=-0.42,95%CI[-0.66,-0.18],Z=3.46,P<0.01);Compared with conventional western medicine,acu⁃point sticking application with conventional western medicine can relieve the clinical symptoms of rheumatoid arthritis such as morning stiffness(MD=-11.95,95%CI[-17.73,-6.17],Z=4.05,P<0.01),arthroncus(MD=-1.75,95%CI[-2.07,-1.43],Z=10.72,P<0.01),joint tenderness(MD=-1.88,95%CI[-2.33,-1.43],Z=8.14,P<0.01).Conclusion Acupoint sticking appli⁃cation can improve the clinical effect of rheumatoid arthritis,and at the same time,multi-center,large-sample,high-quality clinical studies are needed in the future.
作者 郭亚丽 李海婷 贾伞伞 文曹丽 张云 GUO Yali;LI Haiting;JIA Sansan;WEN Caoli;ZHANG Yun(College of Nursing Fujian University of Traditional Chinese Medicine,Fuzhou,FuJian,350100;Department of Nursing,Luoyang Orthopedic-Traumatological Hospital of Henan Province,Luoyang Henan,471000)
出处 《中西医结合护理》 2021年第1期50-55,共6页 Chinese Journal of Integrative Nursing
基金 河南省中医药科学研究专项课题(2017ZY2083)。
关键词 关节炎 类风湿 穴位贴敷 META分析 随机对照试验 arthritis rheumatoid acupoint sticking therapy Meta analysis randomized controlled trials
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