摘要
目的 探究Cook球囊引产与米索前列醇片引产的临床疗效。方法 选取2019年12月—2021年12月该院300例足月引产孕妇,根据是否使用Cook宫颈扩张球囊促宫颈成熟将其分为研究组(应用Cook宫颈扩张球囊促宫颈成熟并引产,n=150)和对照组(采用米索前列醇片促进宫颈成熟并引产,n=150)。比较二组中无合并症孕妇、有妊娠合并症孕妇:妊娠期糖尿病(GDM)、妊娠期高血压(GH)、子痫前期(PE)孕妇促宫颈成熟前后的宫颈Bishop评分、分娩方式、促宫颈成熟成功率、第一产程时间、围生儿结局(胎儿窘迫、新生儿窒息)、引产过程、引产结局及不良事件(宫颈裂伤、产后出血、产后盆腔感染、羊水污染、羊水栓塞)发生率。结果 研究组无合并症、GDM、GH、PE孕妇治疗后宫颈Bishop评分高于对照组无合并症、GDM、GH、PE孕妇(P<0.05);研究组无合并症孕妇剖宫产率(10.31%)低于对照组无合并症孕妇(30.10%)(P<0.05);研究组无合并症孕妇促宫颈成熟成功率(100.00%)高于对照组无合并症孕妇(83.50%)(P<0.05);研究组无合并症、GDM、GH、PE孕妇第一产程时间短于对照组无合并症、GDM、GH、PE孕妇(P<0.05);研究组无合并症、GDM、GH、PE孕妇围生儿Apgar评分、不良结局发生率与对照组无合并症、GDM、GH、PE孕妇比较,差异无统计学意义(P>0.05);研究组无合并症孕妇不良事件发生率(7.22%)低于对照组无合并症孕妇(16.50%)(P<0.05)。结论 Cook球囊应用于足月引产孕妇,能获得较米索前列醇片引产更好的临床效果,且能提高引产安全性。
Objective To explore the clinical efficacy of Cook balloon induction of labor and misoprostol tablets.Methods Three hundred pregnant women with full-term labor induction in our hospital from December 2019 to December 2021 were selected and divided into study groups according to whether the Cook cervical dilation balloon was used to promote cervical ripening(using Cook cervical dilation balloon to promote cervical ripening and labor induction,n=150) and the control group(using misoprostol tablets to promote cervical ripening and induce labor,n=150).The cervical Bishop score,mode of delivery,success rate of cervical ripening,time of first stage of labor,perinatal period of pregnant women without comorbidities,gestational diabetes mellitus(GDM),gestational hypertension(GH),and preeclampsia(PE) before and after treatment were compared between the two groups Infant outcomes(fetal distress,neonatal asphyxia),induction process,induction outcomes,and incidence of adverse events(cervical laceration,postpartum hemorrhage,postpartum pelvic infection,amniotic fluid contamination,amniotic fluid embolism).Results The cervical Bishop score of pregnant women without comorbidities,GDM,GH,PE in the study group after treatment was higher than that in the control group without comorbidities,GDM,GH,PE pregnant women(P<0.05);The incidence of adverse events in pregnant women without comorbidities in the study group(7.22%) was lower than that in pregnant women without comorbidities(16.50%) in the control group(P<0.05).Conclusion Cook balloon used in term labor induction pregnant women can obtain better clinical effect than misoprostol tablet for labor induction,and can improve the safety of labor induction.
作者
童玲玲
崔文华
刘雪芹
高静
TONG Lingling;CUI Wenhua;LIU Xueqin;GAO Jing(The fourth Hospital,Shijiazhuang 050000,China)
出处
《中国煤炭工业医学杂志》
2022年第6期643-649,共7页
Chinese Journal of Coal Industry Medicine
基金
2021年度河北省医学科学研究课题计划(编号:20211533)。
