摘要
慢性乙型肝炎的形成和进展与肠道菌群密切相关,肠道菌群分泌物质信息分子通过脉络丛和肠上皮细胞膜上的受体,将信号转导到细胞内引起联动反应。肠道神经元又与脑迷走神经的突触相连,直接接触联络肠道菌群,构成“脑-神经系统-肠道菌群”的信息传导。基于“见肝之病,知肝传脾,当先实脾”理念的疏肝健脾法,通过调节“脑-肠-菌”功能轴发挥治疗作用,调节“肝主疏泄”功能失调的状态,在改善肝郁脾虚证慢性乙型肝炎患者的临床症状的同时,还可以对脑-肠轴产生一定的影响。
The formation and progression of chronic hepatitis B are closely related to intestinal flora.The information molecules secreted by intestinal flora transduce signals into cells through receptors on choroid plexus and intestinal epithelial cell membrane to cause linkage reaction.Intestinal neurons are connected with the synapse of brain vagus nerve and directly contact the intestinal flora,forming the information transmission of“brain nervous system intestinal flora”.Based on the concept of“seeing the disease of the liver,knowing the liver to transfer the spleen and strengthening the spleen first”,the method of soothing the liver and strengthening the spleen can play a therapeutic role by adjusting the functional axis of“brain intestine bacteria”and adjust the state of functional imbalance of“liver dominating catharsis”,which can not only improve the clinical symptoms of patients with chronic hepatitis B with liver depression and spleen deficiency syndrome,but also have a certain impact on the brain intestine axis.
作者
李薇
程宁
李梅
李吉彦
LI Wei;CHENG Ning;LI Mei;LI Jiyan(Department of Traditional Chinese Medicine,Dalian Public Health Clinical Center,Liaoning Province,Dalian 116031,China;Department of Traditional Chinese Medicine,Dalian Hospital of Traditional Chinese Medicine,Liaoning Province,Dalian 116031,China)
出处
《中国中医药现代远程教育》
2023年第5期136-138,共3页
Chinese Medicine Modern Distance Education of China
基金
辽宁省自然科学基金指导项目【No.201800260】。
关键词
“脑-肠-菌”轴
疏肝健脾法
慢性乙型肝炎
“brain-intestinal-bacteria”axis
soothing the liver and invigorating the spleen method
chronic hepatitis B
