摘要
肝癌是一种严重威胁人类生命健康的常见肿瘤,由于肝癌早期起病隐匿,缺乏特异症状,且常规检查难以筛查出早期肝癌,临床上肝癌的诊断多处于晚期。晚期肝癌可选择的治疗手段少、预后差、复发率高,导致肝癌病死率高,因此早期诊断尤为重要。目前广泛应用于临床的肝癌无创筛查缺少足够的灵敏度及特异度,迫切需要寻找更可靠的诊断方法。本文就肝癌无创早期诊断的研究进展进行综述,为提高肝癌早期诊断率提供参考。
Liver cancer is a common tumor that seriously threatens human life and health.Given that the early onset of liver cancer is insidious and lacks specific symptoms,hence it is difficult to screen through routine examination.Thus,clinical diagnosis of liver cancer is mostly in the advanced stage.However,advanced liver cancer has few treatment options,poor prognosis and high relapse rate,thereby causing a high mortality rate.Therefore,early diagnosis of liver cancer is particularly important.Currently,non-invasive screening of liver cancer widely used in clinical setups lacks sufficient sensitivity and specificity,hence,a more reliable diagnostic method needs to be found urgently.This article reviews the research progress of noninvasive early diagnosis of liver cancer to provide a reference for raising the early diagnosis rate of liver cancer.
作者
卢慧
谢正元
LU Hui;XIE Zhengyuan(Medical College of Nanchang University,Nanchang 330006,China;Department of Gastroenterology,The Second Affiliated Hospital of Nanchang University,Nanchang 330006,China)
出处
《肿瘤防治研究》
CAS
2023年第1期75-80,共6页
Cancer Research on Prevention and Treatment
基金
国家自然科学基金项目(81860119)
江西省自然科学基金重点项目(20212ACB206017)
江西省科技重点研发项目(20203BBG73044)
江西省教育厅科学技术研究项目(GJJ200193)。
关键词
肝癌
早期诊断
无创诊断
生物标志物
成像技术
Liver cancer
Early diagnosis
Noninvasive diagnosis
Biomarkers
Imaging techniques
