摘要
目的分析广东省某第三代核电站运行后其放射工作人员的放射性损伤敏感指标的异常情况,为促进下一步放射工作人员的职业健康管理提供依据。方法采用双向队列研究(2019—2021年),对暴露组(453人)及对照组(160人)职业健康检查的放射性损伤敏感指标进行对比分析。结果2021年暴露组的FT3(5.57±0.56)pmol/L水平高于对照组(5.42±0.60)pmol/L,差异有统计学意义(t=0.59,P<0.05)。2019—2021年暴露组3年的血小板、血红蛋白、血清游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、超敏促甲状腺素(TSH)平均水平差异有统计学意义(P<0.05),其中FT3、FT4呈先升后降趋势,TSH呈下降趋势。结论长期接触低剂量核电站电离辐射会对放射工作人员的血小板、血红蛋白、FT3、FT4、TSH检查结果有影响,其中对甲状腺功能的影响相对明显,并有甲状腺功能降低的发展趋势。
Objective To analyze the abnormality of radiation damage sensitive indices in radiation workers after operation of a third-generation nuclear power plant in Guangdong Province,China,and to provide a basis for promoting the occupational health management of radiation workers.Methods A two-way cohort study(2019—2021)was conducted to compare the radiation sensitive indices of occupational health examination in the exposed group(453 subjects)and the control group(160 subjects).Results In 2021,the free triiodothyronine(FT3)level of the exposed group was significantly higher than that of the control group[(5.57±0.56)pmol/L vs(5.42±0.60)pmol/L,t=0.59,P<0.05].From 2019 to 2021,the exposed group showed significant changes in the average levels of platelet,hemoglobin,FT3,free thyroxine(FT4),and thyroid-stimulating hormone(P<0.05);FT3 and FT4 first increased and then decreased,while TSH decreased continuously.Conclusion Long-term exposure to low-dose ionizing radiation from nuclear power plants can affect the platelet,hemoglobin,FT3,FT4,and thyroid-stimulating hormone of radiation workers,and the effect is relatively prominent on thyroid function by causing a tendency to hypothyroidism.
作者
施毅明
黄福永
陈碧茵
赵超婷
刘静文
SHI Yiming;HUANG Fuyong;CHEN Biyin;ZHAO Chaoting;LIU Jingwen(Jiangmen Institute of Occupational Disease Prevention and Control,Jiangmen 529000 China)
出处
《中国辐射卫生》
2022年第6期708-712,共5页
Chinese Journal of Radiological Health
基金
江门市卫生健康局科研项目(21A027)。
关键词
核电站
放射工作人员
职业健康
Nuclear power plant
Radiation workers
Occupational health
