摘要
目的分析在确诊为缺血性脑血管病患者的临床治疗中,神经介入治疗方案产生的临床效果。方法研究共计纳入700例缺血性脑血管病患者,收治时间范围为2021年1月至2021年12月,以随机表数字法分进行分组,包括分为参照组和实验组(每组350例)。参照组在进行基础治疗的同时以纤溶酶原激活药物进行治疗,实验组在参照组基础上再展开神经介入治疗,对组间血管狭窄情况治疗前后的变化、血管内皮功能治疗前后的变化及神经功能治疗前后的变化进行观察,并且比较组间治疗疗效差异。结果实验组缺血性脑血管病患者血管狭窄情况治疗前显示其Vd、Vs以及血管狭窄率和参照组对比差异均无统计学意义(P>0.05),治疗30d后显示实验组Vd指标明显低于参照组,Vs指标明显低于参照组,血管狭窄率明显低于参照组(P均<0.05)。实验组缺血性脑血管病患者血管内皮功能治疗前显示其FMD以及ABI指标和参照组对比差异均无统计学意义(P>0.05),神经功能NIHSS评分和参照组对比差异无统计学意义(P>0.05);治疗30d后显示实验组FMD指标明显高于参照组,ABI指标明显低于参照组,NIHSS评分明显低于参照组(P均<0.05)。实验组治疗30d后临床疗效的总有效率明显高于参照组(P<0.05)。结论在确诊为缺血性脑血管病患者的临床治疗中,神经介入治疗具有良好的临床治疗应用价值,不仅对患者血管狭窄情况可以带来良好的改善作用,帮助患者有效降低血管内皮功能损害,而且还可以进一步加快患者神经功能恢复,更有利于提高疾病治疗效果。
Objective To analyze the clinical effect of neurointerventional therapy in the clinical treatment of patients diagnosed with ischemic cerebrovascular disease.Methods A total of 700 patients with ischemic cerebrovascular disease were enrolled from January 2021 to December 2021,and were grouped by random table numerical method,including reference group and experimental group(350 cases in each group).The control group was treated with plasminogen-activating drugs at the same time as the basic treatment,and the experimental group carried out neurointerventional therapy on the basis of the reference group,and the changes before and after treatment of vascular stenosis,before and after vascular endothelial function treatment,and changes before and after neurological function treatment were observed,and the differences in treatment efficacy between groups were compared.Results There was no significant difference between Vd,Vs and vascular stenosis rates in the experimental group and the reference group(P>0.05)before treatment,and after 30 days of treatment,the Vd index of the experimental group was significantly lower than that of the reference group,the Vs index was significantly lower than that of the reference group,and the stenosis rate of vascular stenosis was significantly lower than that of the reference group(P<0.05).Before treatment with vascular endothelial function in the experimental group,there was no significant difference in FMD,ABI index and the control group(P>0.05),and there was no significant difference between the neurological NIHSS score and the reference group(P>0.05).The total effective rate of clinical efficacy in the experimental group after 30 days of treatment was significantly higher than that in the control group(P<0.05).Conclusion In the clinical treatment of patients diagnosed with ischemic cerebrovascular disease,neurointerventional therapy has good clinical therapeutic application value,which can not only bring good improvement to the patient’s vascular stenosis,help the patient effectively reduce the damage of vascular endothelial function,but also further accelerate the recovery of the patient’s neurological function,which is more conducive to improving the treatment effect of the disease.
作者
郭彦俊
温昌明
GUO Yan-jun;WEN Chang-ming(Neurocerebrovascular Disease Interventional Ward,Nanyang Central Hospital,Nanyang 473000,Henan Province,China)
出处
《罕少疾病杂志》
2023年第2期19-20,共2页
Journal of Rare and Uncommon Diseases
关键词
缺血性脑血管病
神经介入治疗
血管狭窄
血管内皮功能
神经功能
治疗效果
Ischemic Cerebrovascular Disease
Neurointerventional Therapy
Vascular Stenosis
Vascular Endothelial Function
Neural Function
Therapeutic Effect
